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Science 10 January 1964:
Vol. 143. no. 3602, pp. 132 - 133
DOI: 10.1126/science.143.3602.132
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Articles

Antibody Suppression by Antigen Heavily Labeled with Iodine-131

Milo M. Webber 1

1 Center for Health Sciences, University of California, Los Angeles

Antibody formation in rabbits was suppressed by tobacco mosaic virus heavily labeled with iodine-131. Animals were injected intravenously with virus containing 0.5 to 4.4 mc of l131 and after a period of 6 days were challenged with a new antigen, ggrglobulin. Most irradiated animals did not produce detectable antibody. No signs of radiation sickness were noted.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)