Thiamine: A Novel Conversion from Thiochrome
Gerald E. Risinger 1 and
Patrick N. Parker 1
1 Department of Chemistry, Louisiana Polytechnic Institute, Ruston
Reaction of thiochrome with with
-chloropropionic acid yields thiamine and acetaldehyde. The reaction seems to proceed by way of a zwitterion intermediate that undergoes decarboxylation and hydrolysis. The biological significance of the reaction cannot yet be evaluated.