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Science 30 August 1963:
Vol. 141. no. 3583, pp. 813 - 814
DOI: 10.1126/science.141.3583.813
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Articles

Dissociation of Homograft Response to Allogeneic versus Xenogeneic Skin Grafts in Irradiated Mice

Marvin L. Tyan 1 and Leonard J. Cole 1

1 Biological and Medical Sciences Division, U.S. Naval Radiological Defense Laboratory, San Francisco 24, California

Lethally x-irradiated (C3H x DBA/2)F1 mice were protected with syngeneic (isogenic) bone marrow and/ or prior treatment with urethan and skin grafted at various times after irradiation. The ability to reject a first-set xenogeneic (heterologous) skin graft with normal vigor returned within 92 days; the first-set response to allogeneic (homologous) grafts was still impaired 350 days after irradiation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Thymus: Its Limited Role in the Recovery of Homograft Response in Irradiated Mice.
M. L. Tyan, L. J. Cole, and W. E. Davis Jr. (1963)
Science 142, 584
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Science. ISSN 0036-8075 (print), 1095-9203 (online)