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Science 26 April 1963:
Vol. 140. no. 3565, pp. 394 - 396
DOI: 10.1126/science.140.3565.394
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Articles

Intracranial Self-Stimulation in Man

M. P. Bishop 1, S. Thomas Elder 1, and Robert G. Heath 1

1 Department of Psychiatry and Neurology, Tulane University School of Medicine, New Orleans, Louisiana

Intracranial self-stimulation techniques, modified for use with neuropsychiatric patients, provide data suggestive of positive and negative reinforcing properties of brief electrical stimulation to various subcortical structures of the human brain.


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