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Science 19 April 1963:
Vol. 140. no. 3564, pp. 308 - 310
DOI: 10.1126/science.140.3564.308

Articles

Carbon Tetrachloride Poisoning in Rats: Alteration in Ribosomes of the Liver

Edward A. Smuckler 1 and Earl P. Benditt 1

1 Department of Pathology, University of Washington, Seattle

Microsomes from livers of albino rats treated with carbon tetrachloride were compared with those from normal rats with respect to their ability to incorporate amino acid. Acute carbon tetrachloride poisoning results in depressed capacity of microsomes to incorporate amino acid. From ultracentrifugal data, there is an apparent dissociation of 79S ribosomes into 54S components.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Actinomycin D: An Effect on Rat Liver Homogenates Unrelated to Its Action on RNA Synthesis.
M. Revel, H. H. Hiatt, and J.-P. Revel (1964)
Science 146, 1311-1313
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Science. ISSN 0036-8075 (print), 1095-9203 (online)