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Science 16 November 1962:
Vol. 138. no. 3542, pp. 820 - 822
DOI: 10.1126/science.138.3542.820
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Articles

X-Ray-Induced Chromosome Aberrations in the Corneal Epithelium of the Chinese Hamster

J. Grant Brewen 1

1 Department of Biology, Johns Hopkins University, Baltimore, Maryland

When the corneal epithelium of the Chinese hamster is irradiated with ionizing radiation in vivo, a rectilinear relationship is observed between the yield of chromosome aberrations and the dose of x-rays within a dose range of 10 to 150 r. There is no threshold effect for chromosome breakage down to the 10-r level. The mean breakage rate of 0.00352 breaks per cell per roentgen is in very close agreement with the data obtained on other mammalian tissues, both in vitro and in vivo.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Effects of X-irradiation on Mouse Palatal Epithelial Chromosomes.
K.W. Malek, L. Pentel, S.J. Piliero, and H. Wishe (1980)
Journal of Dental Research 59, 638-643
   Abstract »    PDF »
Effects of Low-Level X Radiation on Chromosomes.
S. C. White (1967)
Journal of Dental Research 46, 1177-1181
   PDF »
The Study of Gene and Chromosome Mutations in Human and Other Mammalian Cell Cultures.
B. Glass (1964)
Cold Spring Harb Symp Quant Biol 29, 177-183
   Abstract »    PDF »


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