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Science 21 September 1962:
Vol. 137. no. 3534, pp. 976 - 977
DOI: 10.1126/science.137.3534.976
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Articles

Ribonucleic Acid in "Transformation" of Lymphoid Cells

J. A. Mannick 1 and R. H. Egdahl 1

1 Strauss Surgical Research Laboratories, Medical College of Virginia, Richmond

When incubated with "reactive" ribonucleic acid extracted from lymph nodes of rabbits immunized by skin homografts, "neutral" lymph node cells from nongrafted rabbits were apparently altered to a state of transpiantation immunity, as manifested by a positive skin reaction upon injection of these cells into the donor of the skin homografts.


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