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Science 29 December 1961:
Vol. 134. no. 3496, pp. 2100 - 2102
DOI: 10.1126/science.134.3496.2100
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Articles

Erythrocyte Automosaicism in Some Persons of Known Genotype

K. C. Atwood 1 and F. Jay Pepper 1

1 Division of Biological Sciences, University of Chicago, Chicago, Illinois

We have estimated the proportions of non-A and non-B erythrocytes in some members of four families in which both parents were blood group AB, including two B homozygotes. The exceptional cell frequencies were not discernibly correlated with age. The B homozygotes had fewer non-B exceptional cells than their AB parents or sibs, but too many to represent independent losses of the B alleles. These results are not in agreement with the simplest expectations based on the mutational hypothesis of automosaicism.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)