Functional Effects of Focused Ultrasound on Mammalian Nerves
Robert R. Young 1 and
Elwood Henneman 1
1 Department of Physiology, Harvard Medical School, and Medical Acoustics Laboratory, Department of Surgery, Massachusetts General Hospital, Boston
Differential blocking of conduction in mammalian nerve fibers has been produced by irradiation of the whole nerve with focused ultrasound. The smallest (C) fibers are the most sensitive; the largest (A-alpha) fibers are the least vulnerable. Fully reversible blocking can be obtained with carefully graded doses of ultrasound.