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Science 29 July 1960:
Vol. 132. no. 3422, pp. 296 - 297
DOI: 10.1126/science.132.3422.296
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Articles

Antithyroid Effects of Aminotriazole

T. H. Jukes 1 and C. B. Shaffer 1

1 American Cyanamid Company, New York 20, New York

Aminotriazole, Like other antithyroid compounds and low-iodine diets, produces adenomatous changes in the thyroid glands of rats when fed continuously for long periods. Such changes are reversible if the antithyroid regime is discontinued. The antithyroid compounds that are naturally present in food are not regarded as causes of cancer.


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