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Science 18 March 1960:
Vol. 131. no. 3403, pp. 828 - 829
DOI: 10.1126/science.131.3403.828
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Articles

Adaptation of Cardiac Output to Peripheral Runoff Studied in Intact Dogs

Heinz P. Pieper 1

1 Department of Physiology, Ohio State University, Columbus

A pump with sinusoidal piston movement was connected to the abdominal aorta of intact anesthetized dogs, causing slow oscillations of arterial blood pressure. Evidence was found for the existence of a mechanism which enables the heart to adjust its output immediately to changes of peripheral outflow.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)