Selective Uptake of Serum Globulins and Glycoproteins by Cells Growing in vitro
H. Naim Kent 1 and
George O. Gey 1
1 Department of Surgery, Johns Hopkins University Medical School, and Department of Pathobiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland
It has been demonstrated in preliminary experiments that two strains of rat tumor cells (WRC-256 and TSAT-72) utilize alpha-2-globulin more selectively than other protein components of human serum. Cells of strain TSAT-72 show some utilization of beta-globulins also. Separate experiments demonstrated the utilization of glycoproteins by both strains.