Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 12 February 1960:
Vol. 131. no. 3398, pp. 410 - 412
DOI: 10.1126/science.131.3398.410
Prev | Table of Contents | Next

Articles

Characteristics of Blood-Brain Barrier to Gamma-Aminobutyric Acid in Neonatal Cat

D. P. Purpura 1 and M. W. Carmichael 1

1 Departments of Neurological Surgery and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York

Systemic ggr-aminobutyric acid produces a rapid, sustained, but transiently reversible blockade of evoked axodendritic excitatory postsynaptic potentials in neonatal cortex when the "barrier" operating to restrict its passage has been altered by various experimental procedures. The data obtained under these conditions indicate the existence of well-developed synaptic pathways in the superficial neuropil of immature cortex.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)