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Science 23 January 1959:
Vol. 129. no. 3343, pp. 212 - 214
DOI: 10.1126/science.129.3343.212-a
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Articles

Failure of Nicotine to Affect Development of Offspring When Administered to Pregnant Rats

LESTER M. GELLER 1

1 Division of Neuropathology, Department of Pathology, College of Physicians and Surgeons, Columbia University, New York

Administration of nicotine to rats at any point in pregnancy has no apparent effect upon completion or duration of pregnancy, or upon body development, litter size, weight, or mortality of offspring. These results differ sharply from the effects in mice reported by others. The possible etiologic significance of anoxia in the malformations reported in mice is discussed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Temporary Uterine Circulatory Arrest as a Cause of Abnormal Fetal Development.
L. E. Feild, S. J. Kreshover, and J. E. Lieberman (1960)
Journal of Dental Research 39, 1240-1247
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Science. ISSN 0036-8075 (print), 1095-9203 (online)