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Science 19 December 1958:
Vol. 128. no. 3338, pp. 1570 - 1571
DOI: 10.1126/science.128.3338.1570
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Articles

New Type Sedative and Soporific Drug

GEORG CRONHEIM 1, JAMES T. GOURZIS 1, and I. M. TOEKES 1

1 Research Division, Riker Laboratories, Northridge, California

Trimethoxybenzoyl-glycine-diethylamide induced in dogs and cats normal sleep without preceding ataxia. A five- to ten-fold increase of the soporific dose resulted in restlessness and disorientation instead of sleep. In man, oral doses of 500 to 1500 mg caused sedation or drowsiness, or both, in half the cases. No spindling or drug-induced artifacts were found in electroencephalographic recordings.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Comparison of a Tranquilizer and a Psychic Energizer: Used in Treatment of Children with Behavioral Disorders.
S. J. Geller (1960)
JAMA 174, 481-484
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Science. ISSN 0036-8075 (print), 1095-9203 (online)