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Published Online November 16, 2006
Science DOI: 10.1126/science.1132514

Reports

Submitted on July 14, 2006
Accepted on October 27, 2006

A Cytokinin Perception Mutant Colonized by Rhizobium in the Absence of Nodule Organogenesis

Jeremy D. Murray 1, Bogumil J. Karas 1, Shusei Sato 2, Satoshi Tabata 2, Lisa Amyot 1, Krzysztof Szczyglowski 1*

1 Agriculture and Agri-Food Canada, Southern Crop Protection and Food Research Centre, 1391 Sandford Street, London, Ontario N5V 4T3, Canada.
2 Kazusa DNA Research Institute, Kisarazu, Chiba, 292-0812, Japan.

* To whom correspondence should be addressed.
Krzysztof Szczyglowski , E-mail: szzyglowskik{at}agr.gc.ca

In legumes, Nod-factor signaling by rhizobia initiates the development of the nitrogen fixing nodule symbiosis, but the direct cell division stimulus that brings about nodule primordia inception in the root cortex remains obscure. Here, we show that Lotus japonicus plants homozygous for a mutation in the HYPERINFECTED 1 (HIT1) locus show abundant infection thread formation but fail to initiate timely cortical cell divisions in response to rhizobial signaling. We demonstrate that the corresponding gene encodes a cytokinin receptor that is required for the activation of the nodule inception regulator Nin and nodule organogenesis.


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