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Science 1 September 1944:
Vol. 100. no. 2592, pp. 200 - 201
DOI: 10.1126/science.100.2592.200
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Articles

EFFECT OF SPINAL FLUID FROM PATIENTS WITH MYASTHENIA GRAVIS ON THE SYNTHESIS OF ACETYLCHOLINE IN VITRO

CLARA TORDA and HAROLD G. WOLFF

Human spinal fluid is a more favorable medium to further the synthesis of acetylcholine in vitro, using enzyme obtained from frog brain, than is serum. Also, since less acetylcholine was synthesized in the presence of spinal fluid from patients with myasthenia gravis than spinal fluid of control subjects, it is probable that at least some of the factors responsible for the decrease and increase of the synthesis of acetylcholine pass into the spinal fluid.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
EFFECT OF AMINO ACIDS ON THE FUNCTION OF THE MUSCLES OF PATIENTS WITH MYASTHENIA GRAVIS.
C. TORDA and H. G. WOLFF (1947)
Arch Intern Med 80, 68-73
   Abstract »    PDF »
Acetylcholine Synthesis.
C. TORDA and H. C. WOLFF (1946)
Science 103, 645-646
   PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)