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Science 1 September 1944:
Vol. 100. no. 2592, pp. 196 - 198
DOI: 10.1126/science.100.2592.196
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Articles

A METHOD OF PROLONGING THE ACTION OF PENICILLIN

MONROE J. ROMANSKY 1 and GEORGE E. RITTMAN 2

1 Captain, Medical Corps, A.U.S.
2 Technician (4th grade), Medical Department, A.U.S.

(1) Single injections of penicillin in beeswax-peanut oil mixture will produce and maintain levels of penicillin in the blood for 7 or more hours.

(2) These mixtures have maintained their potency at room, incubator and refrigerator temperatures for 30 to 62 days and show no signs of deterioration to date.

(3) Eleven of twelve patients with gonorrhoea have been cured by a single injection of penicillin beeswaxpeanut oil mixture.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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TREATMENT OF SYPHILIS WITH PENICILLIN INJECTION IN OIL AND WAX U. S. P. Analysis of One Hundred and Fifty-Three Cases.
J. E. RAUSCHKOLB, H. N. COLE, B. Held, M. H. Gustafson, J. H. Bowen, and M. Utterback (1949)
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A NEW VEHICLE FOR PARENTERAL REPOSITORY PENICILLIN THERAPY.
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PENICILLIN THERAPY OF YAWS AND SEROLOGIC RESULTS.
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DYNAMICS OF THE ACTION OF PENICILLIN: Time-Dose Relationship in Human Streptococcic Disease.
E. JAWETZ (1948)
Arch Intern Med 81, 203-208
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SYPHILIS: A Review of the Recent Literature.
F. W. REYNOLDS and J. E. MOORE (1946)
Arch Intern Med 78, 733-769
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Administration of Streptomycin in Peanut Oil and Beeswax and in Solvecillin.
J. A. KOLMER, A. BONDI JR., H. F. WARNER, and C. DIETZ (1946)
Science 104, 315-317
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USE OF CURARE IN OIL IN TREATMENT OF SPASTICITY FOLLOWING INJURY OF THE SPINAL CORD.
E. B. SCHLESINGER (1946)
Arch Neurol Psychiatry 55, 530-534
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Blood Levels of Penicillin After Oral Administration With Various Antacids.
L. D. SEAGER (1946)
Science 103, 353-355
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ORAL ADMINISTRATION OF PENICILLIN.
A. L. BARACH, B. GARTHWAITE, E. T. OPPENHEIMER, J. FORMAN, and H. OSBURG (1945)
Science 102, 247-250
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PENICILLIN IN IODIZED OIL FOR INSTILLATION INTO THE LUNGS.
M. J. ROMANSKY, D. J. DUGAN, and G. E. RITTMAN (1945)
Science 102, 255-256
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INCREASING AND PROLONGING BLOOD PENICILLIN CONCENTRATIONS FOLLOWING INTRAMUSCULAR ADMINISTRATION.
J. BRONFENBRENNER and C. B. FAVOUR (1945)
Science 101, 673-674
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ORAL PENICILLIN.
W. MCDERMOTT, P. A. BUNN, M. BENOIT, R. DUBOIS, and W. HAYNES (1945)
Science 101, 228-229
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MAINTENANCE OF THE BLOOD LEVEL OF PENICILLIN AFTER INTRAMUSCULAR INJECTION.
W. M. PARKINS, M. WILEY, J. CHANDY, and H. A. ZINTEL (1945)
Science 101, 203-205
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ORAL ADMINISTRATION OF PENICILLIN IN OIL.
R. L. LIBBY (1945)
Science 101, 178-180
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PROLONGATION OF PENICILLIN ACTIVITY BY MEANS OF ADRENALIN.
R. T. FISK, A. G. FOORD, and G. ALLES (1945)
Science 101, 124-125
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INTERACTION BETWEEN CRYSTALLINE PENICILLIN AND HUMAN PLASMA PROTEINS.
B. F. CHOW and C. M. MCKEE (1945)
Science 101, 67-68
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PENICILLIN X: SUCCESSFUL TREATMENT OF GONORRHEA WITH A SINGLE INTRAMUSCULAR INJECTION.
H. WELCH, L. E. PUTNAM, W. A. RANDALL, and R. P. HERWICK (1944)
JAMA 126, 1024
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PROLONGING EFFECTIVE PENICILLIN ACTION.
M. TRUMPER and A. M. HUTTER (1944)
Science 100, 432-434
   Abstract »    PDF »
PROLONGING THE ACTION OF PENICILLIN.
(1944)
JAMA 126, 435
   Abstract »    PDF »


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