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Science 22 August 2008:
Vol. 321. no. 5892, pp. 1092 - 1095
DOI: 10.1126/science.1160770


Grueneberg Ganglion Cells Mediate Alarm Pheromone Detection in Mice
Julien Brechbühl, Magali Klaey, Marie-Christine Broillet

Supporting Online Material

This supplement contains:
Materials and Methods
Figs. S1 to S8
References

Download supplement

This file is in Adobe Acrobat PDF format.

Other Supporting Online Material for this manuscript includes the following: (available at www.sciencemag.org/cgi/content/full/321/5892/1092/DC1)
Movies S1 and S2

Movie s1
The presence of AP induces typical freezing behavior in the control mouse. Photographs taken every 5 s for the first 45 s of the movie S1 are presented (t0-t45). (A) Characteristic exploring activity of a representative control mouse in the presence of ACSF in the container (white box in the lower right corner). (B) When AP are added to ACSF, the behavior of the mouse dramatically changes, continuous freezing occurs.

Movie s2
Complete degeneration of GG cells after axotomy induces a loss of AP sensitivity. Photographs taken every 5 s for the first 45 s of the movie S2 are presented (t0- t45). (A) Characteristic exploring activity of a representative axotomized (Axo) mouse in the presence of ACSF in the container (white box in the lower right corner). (B) When AP are added to ACSF, the behavior of the mouse does not change, no freezing occurs. A continuous exploration of the area is recorded.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)