Ongoing in Vivo Experience Triggers Synaptic Metaplasticity in the Neocortex
Roger L. Clem, Tansu Celikel, Alison L. Barth

Supporting Online Material

This supplement contains:
Materials and Methods
Figs. S1 to S6
References

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Other Supporting Online Material for this manuscript includes the following:
(available at www.sciencemag.org/cgi/content/full/319/5859/101/DC1)
Movies S1 and S2

Movie s1
Acquisition of associative tactile conditioning task. An example raw data set (animal #85) recorded during CS-US training. Frames corresponding to trial onset, CS and US presentations are marked with flashing light emitting diodes (upper light is CS; lower light is US) at 625 nm, at and beyond which wavelength mice have impaired vision.

Movie s2
Acquisition of associative tactile conditioning requires passively delivered whisker deflections. An example raw data set (animal #79) recorded during CS-US training. The animal was not implanted with a metal microrod therefore whisker of interest was not deflected during CS presentation. All other procedures were identical to the ones described for CS-US pairing (see Supplemental Materials and Methods and Supplemental Movie 1.).

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