Inferring Nonneutral Evolution from Human-Chimp-Mouse Orthologous Gene Trios Andrew G. Clark, Stephen Glanowski, Rasmus Nielsen, Paul D. Thomas, Anish Kejariwal, Melissa A. Todd, David M. Tanenbaum, Daniel Civello, Fu Lu, Brian Murphy, Steve Ferriera, Gary Wang, Xianqgun Zheng, Thomas J. White, John J. Sninsky, Mark D. Adams, and Michele Cargill

This supplement contains:

Materials and Methods
Tables S1 to S3
Databases S1 and S2

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Databases S1 and S2. Text-format data tables (packaged as compressed archives of text files, in *.zip format; users should download the compressed archive to their machine and decompress the file on their local hard drive, using the instructions below).
      Database S1 -- 7,645 text files, packaged in compressed archive (9.3 MB compressed; 41.0 MB unpacked)
      Database S2 -- single text file, packaged in compressed archive (1.0 MB compressed; 3.4 MB unpacked)

Instructions for downloading and decompressing Databases S1 and S2:

1. Create a temporary folder on your machine's hard drive.
2. Save the compressed archive to the temporary folder you created, using the links above.
3. Decompress the compressed file in the temporary folder using decompression software such as WinZip (Windows; www.winzip.com) or StuffIt Expander (Windows and Mac; www.stuffit.com).
   
4. The text files can be opened and viewed using your Web browser, word processing software, or any text editor.