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Science 13 July 2001:
Vol. 293. no. 5528, pp. 300 - 303
DOI: 10.1126/science.1061154


Abstract
Full Text
Impairment of Mycobacterial But Not Viral Immunity by a Germline Human STAT1 Mutation
Stéphanie Dupuis, Catherine Dargemont, Claire Fieschi, Nicolas Thomassin, Sergio Rosenzweig, Jeff Harris, Steven M. Holland, Robert D. Schreiber, and Jean-Laurent Casanova

Supplementary Material

Supplemental Figure 1. Serine phosphorylation of STAT-1 in EBV-B cells from a control (C) and the patient (P) stimulated (IFN) or not stimulated (NS) with IFN( or IFN( (1 × 105 IU/ml; 30 min). Cell lysates were immunoprecipitated with an anti-STAT-1-specific mAb and immunoblotted with an anti-STAT-1-phospho-serine-727-specific antibody (Phospho-Ser 727 STAT-1 Ab), an anti-phospho-serine antibody (Phospho-Ser Ab) or an anti-STAT-1-specific mAb (STAT-1 mAb).


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