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Science 17 November 2000:
Vol. 290. no. 5495, pp. 1351 - 1354
DOI: 10.1126/science.290.5495.1351


Abstract
Full Text
Protection Against Cutaneous Leishmaniasis Resulting from Bites of Uninfected Sand Flies
Shaden Kamhawi, Yasmine Belkaid, Govind Modi, Edgar Rowton, and David Sacks

Supplementary Material

 

Supplemental Table 1. Feeding success of infected sand flies on naïve and pre-exposed mice.
Percent of blood-fed flies
Mouse strain
NaïvePre-exposed
BALB/c16.8 (120)*25.0 (120)
C57BL/617.1 (120)11.3 (120)
C57BL/655.7 ( 70)46.0 ( 90)
C57BL/643.1 (140)46.7 (140)
C57BL/665.1 (120)72.3 (120)
*Total number of exposed flies.


Supplemental Figure 1. The composition of leukocytes in a homogenate of the entire ear dermis (22) of naïve and pre-exposed mice 24 hours after uninfected sand fly bites. Mice were given a single intraperitoneal injection with GK1.5 (antibody to CD4) or R35-38 (isotype control) 24 hours before sand fly bites. Cell types are shown as follows: CD4+ T cells (solid bar); macrophages (open bar); dendritic cells (hatched bar); and eosinophils (dotted bar).


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Science. ISSN 0036-8075 (print), 1095-9203 (online)