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BAX and BAK Regulation of Endoplasmic Reticulum Ca2+: A Control Point for
Apoptosis
Luca Scorrano, Scott A. Oakes, Joseph T. Opferman, Emily H. Cheng, Mia D. Sorcinelli, Tullio Pozzan, Stanley J.
Korsmeyer
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Supporting Online Material
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This supplement contains:
Materials and Methods
Figs. S1 to S7
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To view these movies, download a QuickTime viewer.
- Movie S1
Real time imaging of mitochondrial Ca2+ uptake in wt (left) and DKO (right)
MEFs. Rhod2 fluorescence was imaged every 500 msec. The frame corresponding to
Thapsigargin addition is kept still for 1 sec.
- Movie S2
Real time mitochondrial membrane potential imaging in wt (left) and DKO
(right) MEFs. An entire sequence of TMRM fluorescence is shown. The frame
corresponding to the addition of arachidonic acid (ArA) is kept still for 1 sec. See Supp.
Fig. 6 legend for more details.
- Movie S3
Real time mitochondrial membrane potential imaging in wt (left) and DKO
(right) MEFs. An entire sequence of TMRM fluorescence is shown. The frames
corresponding to the addition of histamine (Hist) and arachidonic acid (ArA) are kept still
for 1 sec. See Supp. Fig. 6 legend for more details.
- Movie S4
Real time mitochondrial membrane potential imaging in wt (left) and DKO
(right) MEFs. An entire sequence of TMRM fluorescence is shown. The frames corresponding to the addition of ionomycin (Iono) and arachidonic acid (ArA) are kept
still for 1 sec. See Supp. Fig. 6 legend for more details.