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Science 3 August 2001
DOI: 10.1126/science.1062961


Abstract
Full Text 		A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA
György Hutvágner, Juanita McLachlan, Amy E. Pasquinelli, Éva Bálint, Thomas Tuschl, Phillip D. Zamore

Supplementary Material

Supplemental Figure 1. Specificity of hybridization probes 2, 3, and 4. Northern hybridization was used to assess the ability of each probe to detect three synthetic RNAs: let-7, a 21 nt RNA corresponding to the 5´ end of the putative pre-let-7 (Fig. 1B), and the anti-sense let-7 RNA that would be generated by symmetric RNase III cleavage of the putative pre-let-7.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)