Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Return to article

Figure 4


Fig. 4. Accumulation of Smo and Ptc1 at cilia of NIH 3T3 cells exposed to 20{alpha}-hydroxycholesterol. (A and C) Localization of cilia (red) and Smo or Ptc1 (green) in cells treated with 10 µM 20{alpha}-hydroxycholesterol or 7{alpha}-hydroxycholesterol for 24 hours. (B) Time course of Smo accumulation at the primary cilium in NIH 3T3 cells treated with 20{alpha}-hydroxycholesterol. (D) Increase in Ptc1 fluorescence in primary cilia after treatment with 20{alpha}-hydroxycholesterol. In (B) and (D), each point shows the mean ± SEM of fluorescence from 10 to 20 cilia. [View Larger Version of this Image (281K JPEG file)]

 


[PowerPoint download feature is available to paid individual subscribers and to registered users at subscribing institutions (register for free).]

You may download the image(s) above for non-profit educational presentation use only, provided no modifications are made to the content. Any use, publication, or distribution of the image(s) beyond that permitted in the sentence above or beyond that allowed by the "Fair Use" limitations (sections 107 and 108) of the US Copyright law requires the prior written permission of AAAS. This permission does not apply to images that are credited to non-AAAS sources. For images credited to non-AAAS entities, you will need to obtain permission from the entity listed in the legend or credit line before making any use of the image(s).




To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)