Figure 2

Fig. 2. Phylogenetic tree for the matrix gene of influenza A viruses from a variety of hosts. Nucleotide sequences were selected from public databases and aligned, after which a maximum likelihood tree was generated using influenza virus A/Equine/Prague/57 (H7N7) as outgroup. Sequences were selected from each host to reflect the longest possible time frame and variation in locations of virus isolation. The avian influenza viruses are divided in an American lineage (pink) and a Eurasian lineage (yellow), and there are no clear patterns of host, temporal, or spatial correlation within these lineages. In contrast, the human influenza A virus lineage (light blue), the Eurasian swine lineage (purple), and the HPAI H5N1 lineage (orange) display clear temporal patterns of virus evolution. [View Larger Version of this Image (107K JPEG file)]

 

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