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Science 31 May 2002:
Vol. 296. no. 5573, pp. 1661 - 1671
DOI: 10.1126/science.1069193


Abstract
Full Text
A Comparison of Whole-Genome Shotgun-Derived Mouse Chromosome 16 and the Human Genome
Richard J. Mural, Mark D. Adams, Eugene W. Myers, Hamilton O. Smith, George L. Gabor Miklos, Ron Wides, Aaron Halpern, Peter W. Li, Granger G. Sutton, Joe Nadeau, Steven L. Salzberg, Robert A. Holt, Chinnappa D. Kodira, Fu Lu, Lin Chen, Zuoming Deng, Carlos C. Evangelista, Weiniu Gan, Thomas J. Heiman, Jiayin Li, Zhenya Li, Gennady V. Merkulov, Natalia V. Milshina, Ashwinikumar K. Naik, Rong Qi, Bixiong Chris Shue, Aihui Wang, Jian Wang, Xin Wang, Xianghe Yan, Jane Ye, Shibu Yooseph, Qi Zhao, Liansheng Zheng, Shiaoping C. Zhu, Kendra Biddick, Randall Bolanos, Arthur L. Delcher, Ian M. Dew, Daniel Fasulo, Michael J. Flanigan, Daniel H. Huson, Saul A. Kravitz, Jason R. Miller, Clark M. Mobarry, Knut Reinert, Karin A. Remington, Qing Zhang, Xiangqun H. Zheng, Deborah R. Nusskern, Zhongwu Lai, Yiding Lei, Wenyan Zhong, Alison Yao, Ping Guan, Rui-Ru Ji, Zhiping Gu, Zhen-Yuan Wang, Fei Zhong, Chunlin Xiao, Chia-Chien Chiang, Mark Yandell, Jennifer R. Wortman, Peter G. Amanatides, Suzanne L. Hladun, Eric C. Pratts, Jeffery E. Johnson, Kristina L. Dodson, Kerry J. Woodford, Cheryl A. Evans, Barry Gropman, Douglas B. Rusch, Eli Venter, Mei Wang, Thomas J. Smith, Jarrett T. Houck, Donald E. Tompkins, Charles Haynes, Debbie Jacob, Soo H. Chin, David R. Allen, Carl E. Dahlke, Robert Sanders, Kelvin Li, Xiangjun Liu, Alexander A. Levitsky, William H. Majoros, Quan Chen, Ashley C. Xia, John R. Lopez, Michael T. Donnelly, Matthew H. Newman, Anna Glodek, Cheryl L. Kraft, Marc Nodell, Feroze Ali, Hui-Jin An, Danita Baldwin-Pitts, Karen Y. Beeson, Shuang Cai, Mark Carnes, Amy Carver, Parris M. Caulk, Angela Center, Yen-Hui Chen, Ming-Lai Cheng, My D. Coyne, Michelle Crowder, Steven Danaher, Lionel B. Davenport, Raymond Desilets, Susanne M. Dietz, Lisa Doup, Patrick Dullaghan, Steven Ferriera, Carl R. Fosler, Harold C. Gire, Andres Gluecksmann, Jeannine D. Gocayne, Jonathan Gray, Brit Hart, Jason Haynes, Jeffery Hoover, Tim Howland, Chinyere Ibegwam, Mena Jalali, David Johns, Leslie Kline, Daniel S. Ma, Steven MacCawley, Anand Magoon, Felecia Mann, David May, Tina C. McIntosh, Somil Mehta, Linda Moy, Mee C. Moy, Brian J. Murphy, Sean D. Murphy, Keith A. Nelson, Zubeda Nuri, Kimberly A. Parker, Alexandre C. Prudhomme, Vinita N. Puri, Hina Qureshi, John C. Raley, Matthew S. Reardon, Megan A. Regier, Yu-Hui C. Rogers, Deanna L. Romblad, Jakob Schutz, John L. Scott, Richard Scott, Cynthia D. Sitter, Michella Smallwood, Arlan C. Sprague, Erin Stewart, Renee V. Strong, Ellen Suh, Karena Sylvester, Reginald Thomas, Ni Ni Tint, Christopher Tsonis, Gary Wang, George Wang, Monica S. Williams, Sherita M. Williams, Sandra M. Windsor, Keriellen Wolfe, Mitchell M. Wu, Jayshree Zaveri, Kabir Chaturvedi, Andrei E. Gabrielian, Zhaoxi Ke, Jingtao Sun, Gangadharan Subramanian, and J. Craig Venter

Supplementary Material


Supplemental table 1. Mouse genes on chromosome 16 without an identifiable human counterpart.

These 14 genes appear to be unique to the mouse. For each transcript the second column gives the confidence of the prediction (Otto is highest, for the "promoted" transcripts 4 is the highest confidence and 1 is the lowest). Promote 2, Promote 3, and Promote 4 correspond to genes with 2 to 4 lines of evidence, respectively, as described in Table 8 of (1). The last column gives protein domain information (if available), the best hit (by BLASTP) for the translation of the transcript (if available) (the expectation value in parentheses), and a Gene Ontology (GO) assignment (if available).

Transcript Confidence Evidence of relationship
mCT15271Otto dbj|BAB27173.1| (AK010774) putative [Mus musculus] (4E-19)
mCT20612OttoAA TRANSFER CLASS 2 (INTERPRO. IPR001917)
mCT55806Promote 2dbj|BAB24709.1| (AK006709) putative [Mus musculus] (8E-12)
mCT18199 Otto ref|NP_081926.1| (NM_027650) RIKEN cDNA 4933405P08 gene [Mus musculus] (5E-77)
mCT9475 Otto
mCT51327Promote 3 dbj|BAB22210.1| (AK002589) putative [Mus musculus] (3E-51); GO: Function>microtubule motor
mCT12188Otto
mCT15750Otto ARG RICH; dbj;BAB30360.1 (AK016649) putative [Mus musculus] (0.0)
mCT15875Ottodbj|BAB29846.1| (AK015438) putative [Mus musculus] (4E-47); GO:location> plasma membrane
mCT9117Otto ref|NP_082881.1| RIKEN cDNA 2410116I05 gene [Mus musculus] (1E-7)
mCT8692Otto dbj|BAB24709.1| (AK006709) putative [Mus musculus] (3E-15)
mCT8997Otto dbj|BAB31472.1| (AK018881) putative [Mus musculus (1E-11)
mCT9728Otto CARBOXYPEPT SER SER (INTERPRO. IPR001563)
mCT18217 Otto





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Science. ISSN 0036-8075 (print), 1095-9203 (online)