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Science 19 October 2007:
Vol. 318. no. 5849, p. 393
DOI: 10.1126/science.1145011
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Technical Comments

Comment on "Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension"

Nader Sanai1,3*, Mitchel S. Berger1, Jose Manuel Garcia-Verdugo2 and Arturo Alvarez-Buylla1,3

1 Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143–0112, USA.
2 Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Apartado 22085, University of Valencia, 46071 Valencia, Spain.
3 Institute of Regenerative Medicine, HSW 1201A, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143–0520, USA.


Figure 1 Fig. 1. (A) Examination of three adult human olfactory tracts in 1-µm plastic sections by electron microscopy revealed no evidence of an open ventricular system. (B) A lumen in the core of the olfactory tract corresponds to a blood vessel surrounded by endothelial cells (arrows) and smooth muscle (*). However, no evidence of ependymal cells or cavities continuous with the ventricular system was observed. [View Larger Version of this Image (97K GIF file)]
 

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Science. ISSN 0036-8075 (print), 1095-9203 (online)