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Science 22 June 2007:
Vol. 316. no. 5832, p. 1698
DOI: 10.1126/science.1138579
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Technical Comments

Response to Comment on "Tequila, a Neurotrypsin Ortholog, Regulates Long-Term Memory Formation in Drosophila"

Thomas Preat1*, Jean-Luc Da Lage2, Laurence Colleaux3, Gérard Didelot1{dagger}, Florence Molinari3, Paul Tchenio4, Elodie Milhiet4, Arnold Munnich3 and Marie-Louise Cariou2

1 Gènes et Dynamique des Systèmes de Mémoire, UMR CNRS 7637, Ecole Supérieure de Physique et de Chimie Industrielles, 10 rue Vauquelin 75005 Paris, France.
2 Evolution, Génomes et Spéciation, UPR CNRS 9034, avenue de la Terrasse 91198 Gif-sur-Yvette Cedex, France.
3 Département de Génétique et Unité de Recherche sur les Handicaps Génétiques de l'Enfant, INSERM U781, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75743 Paris Cedex 15, France.
4 Laboratoire Aimé Cotton, UPR CNRS 3321, Bâtiment 505, 91405 Orsay Cedex, France.


Figure 1 Fig. 1. Phylogenetic relationships obtained through NJ analysis based on the trypsin domain amino acid sequences. Note that PRSS12 encodes neurotrypsin. Bootstrap supports are indicated on the branches, and the tree has been rooted using the midpoint method. The scale represents the mean number of substitutions per amino acid. [View Larger Version of this Image (13K GIF file)]
 

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Science. ISSN 0036-8075 (print), 1095-9203 (online)