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Science 1 June 1990:
Vol. 248. no. 4959, pp. 1058 - 1060
DOI: 10.1126/science.2111582
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Articles

Deciphering Alzheimer's disease: the amyloid precursor protein yields new clues

DJ Selkoe

No abstract or summary view of this item is available. To view the full-text version, follow this link.

Article topics:

  • Biochemistry..Proteolytic Enzymes
  • Medicine..Alzheimer Disease
  • Biochemistry..Serine
  • Biochemistry..Polypeptides
  • Developmental Biology..Down Syndrome
  • Physiology..Neuroglia
  • Pharmacology..Protease Inhibitors


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
AATF Inhibits Aberrant Production of Amyloid {beta} Peptide 1-42 by Interacting Directly with Par-4.
Q. Guo and J. Xie (2004)
J. Biol. Chem. 279, 4596-4603
   Abstract »    Full Text »    PDF »
Delivery across the Blood-Brain Barrier of Antisense Directed against Amyloid beta : Reversal of Learning and Memory Deficits in Mice Overexpressing Amyloid Precursor Protein.
W. A. Banks, S. A. Farr, W. Butt, V. B. Kumar, M. W. Franko, and J. E. Morley (2001)
J. Pharmacol. Exp. Ther. 297, 1113-1121
   Abstract »    Full Text »
Permeability of the Blood-Brain Barrier to Albumin and Insulin in the Young and Aged SAMP8 Mouse.
W. A. Banks, S. A. Farr, and J. E. Morley (2000)
J. Gerontol. A Biol. Sci. Med. Sci. 55, 601B-606
   Abstract »    Full Text »
Caspase-2 Mediates Neuronal Cell Death Induced by beta -Amyloid.
C. M. Troy, S. A. Rabacchi, W. J. Friedman, T. F. Frappier, K. Brown, and M. L. Shelanski (2000)
J. Neurosci. 20, 1386-1392
   Abstract »    Full Text »    PDF »
An Introduction to the Molecular Genetics of Neurological Disease: Recent Advances.
R. N. Rosenberg (1993)
Arch Neurol 50, 1123-1128
   Abstract »    PDF »
Neurology.
R. J. Joynt (1991)
JAMA 265, 3134-3135
   Abstract »    PDF »
Alzheimer's pathology explored.
J Marx (1990)
Science 249, 984-986
   PDF »
The Neuroprotective Effects of Phytoestrogens on Amyloid beta Protein-induced Toxicity Are Mediated by Abrogating the Activation of Caspase Cascade in Rat Cortical Neurons.
C.-N. Wang, C.-W. Chi, Y.-L. Lin, C.-F. Chen, and Y.-J. Shiao (2001)
J. Biol. Chem. 276, 5287-5295
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)