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Science 29 June 1973:
Vol. 180. no. 4093, pp. 1332 - 1339
DOI: 10.1126/science.180.4093.1332

Articles

Atherosclerosis and the Arterial Smooth Muscle Cell

Russell Ross and John A. Glomset

No abstract or summary view of this item is available. To view the full-text version, follow this link.

Article topics:

  • Earth Sciences..Petroleum
  • Sociology..Safety


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Differentiation of Vascular Smooth Muscle Cells and the Regulation of Protein Kinase C-{alpha}.
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Localization of PDGF-B protein in macrophages in all phases of atherogenesis.
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Science 248, 1009-1012
   Abstract »    PDF »
Intimal Hyperplasia: Evolving Concepts of Pathophysiology and Therapy.
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Perspectives in Vascular Surgery and Endovascular Therapy 2, 97-111
   PDF »
Observations of Early Atherogenesis with Calcification Following Aortic Deendothelialization in Rabbits Maintained on a Normal Diet.
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Vascular and Endovascular Surgery 23, 27-33
   Abstract »    PDF »
Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension.
R. Mecham, L. Whitehouse, D. Wrenn, W. Parks, G. Griffin, R. Senior, E. Crouch, K. Stenmark, and N. Voelkel (1987)
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Clinical Laboratory Assessment of Atherosclerosis Role of Hyperlipidaemia and Hyperactive Platelets.
A. P. Chitre and D.S. Velaskar (1986)
Angiology 37, 306-313
   Abstract »    PDF »
Hormonal requirements for growth of arterial smooth muscle cells in vitro: and endocrine approach to atherosclerosis.
R Weinstein, M. Stemerman, and T Maciag (1981)
Science 212, 818-820
   Abstract »    PDF »
Coronary Vasospasm: Observations Linking the Clinical Spectrum of Ischemic Heart Disease to the Dynamic Pathology of Coronary Atherosclerosis.
B. G. Brown (1981)
Arch Intern Med 141, 716-722
   Abstract »    PDF »
Small-Vessel Disease: Diabetic Microangiopathy.
J. R. Williamson and C. Kilo (1980)
Angiology 31, 448-454
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Selective phospholipid adsorption and atherosclerosis.
N. Gershfeld (1979)
Science 204, 506-508
   Abstract »    PDF »
Fatty acids and their prostaglandin derivatives: inhibitors of proliferation in aortic smooth muscle cells.
J. Huttner, E. Gwebu, R. Panganamala, G. Milo, D. Cornwell, H. Sharma, and J. Geer (1977)
Science 197, 289-291
   Abstract »    PDF »
Development of Atherosclerosis in a Saphenous Vein Coronary Bypass Graft.
J. FARRY, G. L. HAMMOND, L. S. COHEN, and S. WOLFSON (1976)
Ann Intern Med 85, 478-479
   Abstract »    PDF »
The Common Hyperlipoproteinemias: An Understanding of Disease Mechanisms and Their Control.
W. R. FISHER and D. H. TRUITT (1976)
Ann Intern Med 85, 497-508
   Abstract »    PDF »
Hyperlipidemia and atherosclerosis.
R Ross and L Harker (1976)
Science 193, 1094-1100
   Abstract »    PDF »
Homogenized Milk and Atherosclerosis.
J. P. Zikakis (1974)
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