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Science 24 February 1956: Vol. 123. no. 3191, pp. 309 - 314 DOI: 10.1126/science.123.3191.309
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Articles
On the Origin of Cancer Cells
Otto Warburg
No abstract or summary view of this item is available. To view the full-text version, follow this link.
Article topics:
- Biochemistry..Fermentation
- Neuroscience..Adenosine
- Medicine..Ascites
- Biochemistry..Oxygen Consumption
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- Succinate inhibition of {alpha}-ketoglutarate-dependent enzymes in a yeast model of paraganglioma.
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Hum. Mol. Genet.
16, 3136-3148
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- Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
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PNAS
104, 19345-19350
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- Targeting Vacuolar H+-ATPases as a New Strategy against Cancer.
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Cancer Res.
67, 10627-10630
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- Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1.
- J.-w. Kim, P. Gao, Y.-C. Liu, G. L. Semenza, and C. V. Dang (2007)
Mol. Cell. Biol.
27, 7381-7393
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- Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.
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J. Cell Biol.
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- Drug Resistance and the Solid Tumor Microenvironment.
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J Natl Cancer Inst
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- Regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Activities by the Poly(ADP-Ribose) Polymerase Family-14.
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Cancer Res.
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- Elevated Expression of DecR1 Impairs ErbB2/Neu-Induced Mammary Tumor Development.
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Mol. Cell. Biol.
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- Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence.
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Am. J. Clinical Nutrition
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- The hyperproliferative endothelial cell phenotype in idiopathic pulmonary arterial hypertension.
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Am J Physiol Lung Cell Mol Physiol
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- A Disturbance in the Force Mitochondrial Mutations in Squamous Cell Carcinoma of the Head and Neck.
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Clin. Cancer Res.
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- Glycogen Synthase Kinase 3{alpha} and 3{beta} Mediate a Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1.
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Mol. Cell. Biol.
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- Activation of a Novel Calcineurin-mediated Insulin-like Growth Factor-1 Receptor Pathway, Altered Metabolism, and Tumor Cell Invasion in Cells Subjected to Mitochondrial Respiratory Stress.
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- The modifier of Min 2 (Mom2) locus: Embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression.
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Genome Res.
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- Silencing of Hypoxia Inducible Factor-1{alpha} by RNA Interference Attenuates Human Glioma Cell Growth In vivo.
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Clin. Cancer Res.
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- Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production.
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PNAS
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- Reproducibility of 18F-FDG microPET Studies in Mouse Tumor Xenografts.
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J. Nucl. Med.
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- Cytokine Stimulation Promotes Glucose Uptake via Phosphatidylinositol-3 Kinase/Akt Regulation of Glut1 Activity and Trafficking.
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Mol. Biol. Cell
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- Adaptation of Energy Metabolism in Breast Cancer Brain Metastases.
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- Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis.
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PNAS
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- Structural and Mechanistic Studies on the Inhibition of the Hypoxia-inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates.
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