Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 16 September 1955:
Vol. 122. no. 3168, pp. 501 - 504
DOI: 10.1126/science.122.3168.501

Articles

Nutrition Needs of Mammalian Cells in Tissue Culture

Harry Eagle

No abstract or summary view of this item is available. To view the full-text version, follow this link.

Article topics:

  • Physiology..Humans
  • Physiology..Mice
  • Biochemistry..Glutamine
  • Oncology..Diet and Nutrition
  • Cell Biology..Mouse Fibroblasts
  • Medicine..Carcinoma


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
D. R. Wise, R. J. DeBerardinis, A. Mancuso, N. Sayed, X.-Y. Zhang, H. K. Pfeiffer, I. Nissim, E. Daikhin, M. Yudkoff, S. B. McMahon, et al. (2008)
PNAS 105, 18782-18787
   Abstract »    Full Text »    PDF »
Potential Role for Astroglial D-Amino Acid Oxidase in Extracellular D-Serine Metabolism and Cytotoxicity.
H. K. Park, Y. Shishido, S. Ichise-Shishido, T. Kawazoe, K. Ono, S. Iwana, Y. Tomita, K. Yorita, T. Sakai, and K. Fukui (2006)
J. Biochem. 139, 295-304
   Abstract »    Full Text »    PDF »
Soluble Vascular Endothelial Growth Factor Receptor 1 Inhibits Edema and Epithelial Proliferation Induced by 17{beta}-Estradiol in the Mouse Uterus.
J. M. Hastings, D. R. Licence, G. J. Burton, D. S. Charnock-Jones, and S. K. Smith (2003)
Endocrinology 144, 326-334
   Abstract »    Full Text »    PDF »
Molecular and functional analysis of glutamine uptake in human hepatoma and liver-derived cells.
B. P. Bode, B. C. Fuchs, B. P. Hurley, J. L. Conroy, J. E. Suetterlin, K. K. Tanabe, D. B. Rhoads, S. F. Abcouwer, and W. W. Souba (2002)
Am J Physiol Gastrointest Liver Physiol 283, G1062-G1073
   Abstract »    Full Text »    PDF »
Exercise-induced immunodepression- plasma glutamine is not the link.
N. Hiscock and B. K. Pedersen (2002)
J Appl Physiol 93, 813-822
   Abstract »    Full Text »    PDF »
Recent Molecular Advances in Mammalian Glutamine Transport.
B. P. Bode (2001)
J. Nutr. 131, 2475S-2485
   Abstract »    Full Text »    PDF »
Glutamine in the Fetus and Critically Ill Low Birth Weight Neonate: Metabolism and Mechanism of Action.
J. Neu (2001)
J. Nutr. 131, 2585S-2589
   Abstract »    Full Text »    PDF »
Glutamine: Role in the Fetus and Low-birthweight Infant.
J. Neu (2000)
NeoReviews 1, e215-221
   Full Text »
E.B. Wilson Lecture, 1998. Eukaryotic RNAs: Once More from the Beginning ....
J. E. Darnell Jr. (1999)
Mol. Biol. Cell 10, 1685-1692
   Full Text »
Uptake of glutamate, not glutamine synthetase, regulates adaptation of mammalian cells to glutamine-free medium.
R. McDermott and M Butler (1993)
J. Cell Sci. 104, 51-58
   Abstract »    PDF »
Inhibition of Cell Growth in vitro by Adenosine 3', 5'-Monophosphate.
W. L. Ryan and M. L. Heidrick (1968)
Science 162, 1484-1485
   Abstract »    PDF »
Sulfur Mustard and X-Rays: Differences in Expression of Lethal Damage.
F. Mauro and M. M. Elkind (1967)
Science 155, 1561-1563
   Abstract »    PDF »
Arrested Protein Synthesis in Polysomes of Cultured Chick Embryo Cells.
R. Soeiro and H. Amos (1966)
Science 154, 662-665
   Abstract »    PDF »
Differentiation in vitro: Effects of Sephadex Fractions of Chick Embryo Extract.
H. G. Coon and R. D. Cahn (1966)
Science 153, 1116-1119
   Abstract »    PDF »
Antibody Synthesis Initiated in vitro by Paired Explants of Spleen and Thymus.
G. C. Saunders and D. W. King (1966)
Science 151, 1390-1391
   Abstract »    PDF »
Eimeria tenella: Cultivation of the Asexual Stages in Cultured Animal Cells.
W. H. Patton (1965)
Science 150, 767-769
   Abstract »    PDF »
Triploidy in a Human Cell Line.
J. D. Regan and J. B. Smith (1965)
Science 149, 1516-1517
   Abstract »    PDF »
In Vitro Culture of Osteoblasts From Otosclerotic Bone.
M. LAWRENCE (1965)
Arch Otolaryngol Head Neck Surg 82, 136-143
   Abstract »    PDF »
Metabolic Controls in Cultured Mammalian Cells: Cultured cells may provide a direct approach to regulation and function in the whole animal.
H. Eagle (1965)
Science 148, 42-51
   Abstract »    PDF »
Cytodifferentiation and Its Controls.
C. Grobstein (1964)
Science 143, 643-650
   PDF »
Ethylene Oxide Sterilization of Tissue Culture Media.
B. L. Brown and R. Fuerst (1963)
Science 142, 1654-1655
   Abstract »    PDF »
Clonal Analysis of Myogenesis: Its relevance to the general problem of the stability of cell-type in cultured animal cells is discussed.
I. R. Konigsberg (1963)
Science 140, 1273-1284
   PDF »
Transplantation of Autologous Canine Thyroid: Transplantation After Preservation at Low Temperature.
G. D. ZUIDEMA and W. D. BURTON (1963)
Arch Surg 86, 246-249
   Abstract »    PDF »
Metabolic Alterations with Senescence of Human Cells: Some Observations in Vitro.
R. S. CHANG (1962)
Arch Intern Med 110, 563-568
   Abstract »    PDF »
Virus Neutralization Test in a Capillary Tube.
D. P. Durand (1962)
Science 138, 448
   Abstract »    PDF »
Autoradiographic Localization of Tritiated Thymidine in Whole-Mount Preparations of Lens Epithelium.
C. V. HARDING, W. L. HUGHES, V. P. BOND, and P. SCHORK (1960)
Arch Ophthalmol 63, 58-65
   Abstract »    PDF »
Amino Acid Metabolism in Mammalian Cell Cultures.
H. Eagle (1959)
Science 130, 432-437
   PDF »
Some Viral Central Nervous System Diseases: Laboratory Studies with Emphasis on Aseptic Meningitis.
N. KHOOBYARIAN, J. DRAPER, A. C. DWYER, Y. K. S. MURTHY, and D. N. WALCHER (1959)
Arch Pediatr Adolesc Med 98, 15-23
   Abstract »    PDF »
Incorporation of Unnatural Pyrimidine Bases into Deoxyribonucleic Acid of Mammalian Cells.
M. L. EIDINOFF, L. CHEONG, and M. A. RICH (1959)
Science 129, 1550-1551
   Abstract »    PDF »
Requirements for Growth of Single Human Cells: "Nonessential" amino acids, notably serine, are necessary and sufficient nutritional supplements.
R. Z. Lockart Jr. and H. Eagle (1959)
Science 129, 252-254
   Abstract »    PDF »
Epidemic of Diarrhea of the Newborn--Nonassociation of Cytopathogenic Agents.
C. S. STULBERG, W. W. ZUELZER, and R. PAGE (1958)
Arch Pediatr Adolesc Med 95, 30-34
   Abstract »    PDF »
Ribosidation as a Means of Activating 6-Azauracil as an Inhibitor of Cell Reproduction.
R. SCHINDLER and A. D. WELCH (1957)
Science 125, 548-549
   PDF »
Dual Requirement of Walker Carcinosarcoma 256 in vitro for Asparagine and Glutamine.
R. E. NEUMAN and T. A. MCCOY (1956)
Science 124, 124-125
   PDF »
Possible Function of Serum Proteins in Tissue Culture.
L. S. VANN (1956)
Science 123, 326-327
   PDF »
The Ontogeny of Divergent Metabolic Patterns in Cells of Identical Genotype.
C. L. Markert (1956)
Cold Spring Harb Symp Quant Biol 21, 339-348
   Abstract »    PDF »
Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing.
K. M. ELGADI, R. A. MEGUID, M. QIAN, W. W. SOUBA, and S. F. ABCOUWER (1999)
Physiol Genomics 1, 51-62
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)