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Science 11 August 2006:
Vol. 313. no. 5788, p. 761
DOI: 10.1126/science.1126765
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Technical Comments

Response to Comment on "Gene Regulatory Networks and the Evolution of Animal Body Plans"

Douglas H. Erwin1,2* and Eric H. Davidson3

Contrary to Coyne's assertions, our paper did not advocate a macromutational innovation of phyla but considered the consequences of the introduction of developmental constraints for the evolution of gene regulatory networks based on recent empirical studies of gene regulatory networks.

1 Department of Paleobiology, MRC-121, National Museum of Natural History, Post Office Box 37012, Washington, DC 20013–7012, USA.
2 Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, NM 87501, USA.
3 Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

* To whom correspondence should be addressed. E-mail: erwind{at}si.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)