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Science 12 May 2006:
Vol. 312. no. 5775, pp. 873 - 875
DOI: 10.1126/science.1123223
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Perspective

Viruses: Making Friends with Old Foes

Trevor Douglas and Mark Young

The study of viruses has traditionally focused on their roles as infectious agents and as tools for understanding cell biology. Viruses are now finding a new expanded role as nanoplatforms with applications in materials science and medicine. Viruses form highly symmetrical monodisperse architectures and are ideal templates for engineering multifunctionality, including multivalent display of surface ligands and encapsulation of inorganic and organic materials. These developments assure that viruses will find applications as versatile nanoscale materials.

Center for Bio-Inspired Nanomaterials, Montana State University, Bozeman, MT 59717, USA.

E-mail: tdouglas{at}chemistry.montana.edu (T.D.); myoung{at}montana.edu (M.Y.)

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Manipulation of the mechanical properties of a virus by protein engineering.
C. Carrasco, M. Castellanos, P. J. de Pablo, and M. G. Mateu (2008)
PNAS 105, 4150-4155
   Abstract »    Full Text »    PDF »
Core-controlled polymorphism in virus-like particles.
J. Sun, C. DuFort, M.-C. Daniel, A. Murali, C. Chen, K. Gopinath, B. Stein, M. De, V. M. Rotello, A. Holzenburg, et al. (2007)
PNAS 104, 1354-1359
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)