Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 4 November 2005:
Vol. 310. no. 5749, pp. 810 - 815
DOI: 10.1126/science.1115807
Prev | Table of Contents | Next

Review

Map Plasticity in Somatosensory Cortex

Daniel E. Feldman1* and Michael Brecht2

Sensory maps in neocortex are adaptively altered to reflect recent experience and learning. In somatosensory cortex, distinct patterns of sensory use or disuse elicit multiple, functionally distinct forms of map plasticity. Diverse approaches—genetics, synaptic and in vivo physiology, optical imaging, and ultrastructural analysis—suggest a distributed model in which plasticity occurs at multiple sites in the cortical circuit with multiple cellular/synaptic mechanisms and multiple likely learning rules for plasticity. This view contrasts with the classical model in which the map plasticity reflects a single Hebbian process acting at a small set of cortical synapses.

1 Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, Room 0357, La Jolla, CA 92093, USA.
2 Department of Neuroscience, Erasmus MC, Postbus 1738, 3000 DR Rotterdam, Netherlands.

* To whom correspondence should be addressed. E-mail: dfeldman{at}ucsd.edu

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Double Dissociation of Spike Timing-Dependent Potentiation and Depression by Subunit-Preferring NMDA Receptor Antagonists in Mouse Barrel Cortex.
A. Banerjee, R. M. Meredith, A. Rodriguez-Moreno, S. B. Mierau, Y. P. Auberson, and O. Paulsen (2009)
Cereb Cortex
   Abstract »    Full Text »    PDF »
Sensory Experience Alters Specific Branches of Individual Corticocortical Axons during Development.
R. M. Bruno, T. T. G. Hahn, D. J. Wallace, C. P. J. de Kock, and B. Sakmann (2009)
J. Neurosci. 29, 3172-3181
   Abstract »    Full Text »    PDF »
Reorganisation of cortical motor and language distribution in human brain.
H W Lee, J S Shin, W R S Webber, N E Crone, L Gingis, and R P Lesser (2009)
J. Neurol. Neurosurg. Psychiatry 80, 285-290
   Abstract »    Full Text »    PDF »
Intrinsic Signal Imaging of Deprivation-Induced Contraction of Whisker Representations in Rat Somatosensory Cortex.
P. J. Drew and D. E. Feldman (2009)
Cereb Cortex 19, 331-348
   Abstract »    Full Text »    PDF »
Increasing Interaction of Amygdalar Afferents with GABAergic Interneurons between Birth and Adulthood.
M. G. Cunningham, S. Bhattacharyya, and F. M. Benes (2008)
Cereb Cortex 18, 1529-1535
   Abstract »    Full Text »    PDF »
Critical Period Plasticity of Axonal Arbors of Layer 2/3 Pyramidal Neurons in Rat Somatosensory Cortex: Layer-Specific Reduction of Projections into Deprived Cortical Columns.
P. Broser, V. Grinevich, P. Osten, B. Sakmann, and D. J. Wallace (2008)
Cereb Cortex 18, 1588-1603
   Abstract »    Full Text »    PDF »
Plasticity of Representational Maps in Somatosensory Cortex Observed by In Vivo Voltage-Sensitive Dye Imaging.
D. J. Wallace and B. Sakmann (2008)
Cereb Cortex 18, 1361-1373
   Abstract »    Full Text »    PDF »
Short-term variations in response distribution to cortical stimulation.
R. P. Lesser, H. W. Lee, W. R. S. Webber, B. Prince, N. E. Crone, and D. L. Miglioretti (2008)
Brain 131, 1528-1539
   Abstract »    Full Text »    PDF »
Circuit and Plasticity Defects in the Developing Somatosensory Cortex of Fmr1 Knock-Out Mice.
I. Bureau, G. M. G. Shepherd, and K. Svoboda (2008)
J. Neurosci. 28, 5178-5188
   Abstract »    Full Text »    PDF »
Dendritic Excitability and Synaptic Plasticity.
P. J. Sjostrom, E. A. Rancz, A. Roth, and M. Hausser (2008)
Physiol Rev 88, 769-840
   Abstract »    Full Text »    PDF »
Developmental presence and disappearance of postsynaptically silent synapses on dendritic spines of rat layer 2/3 pyramidal neurons.
G. Busetto, M. J. Higley, and B. L. Sabatini (2008)
J. Physiol. 586, 1519-1527
   Abstract »    Full Text »    PDF »
Internal body state influences topographical plasticity of sensory representations in the rat gustatory cortex.
R. Accolla and A. Carleton (2008)
PNAS 105, 4010-4015
   Abstract »    Full Text »    PDF »
Temporal Dynamics of Plastic Changes in Human Primary Somatosensory Cortex after Finger Webbing.
M. L. Stavrinou, S. Della Penna, V. Pizzella, K. Torquati, F. Cianflone, R. Franciotti, A. Bezerianos, G. L. Romani, and P. M. Rossini (2007)
Cereb Cortex 17, 2134-2142
   Abstract »    Full Text »    PDF »
Plasticity of inwardly rectifying conductances following a corticospinal lesion in human subjects.
S. K. Jankelowitz, J. Howells, and D. Burke (2007)
J. Physiol. 581, 927-940
   Abstract »    Full Text »    PDF »
Layer- and Cell-Type-Specific Effects of Neonatal Whisker-Trimming in Adult Rat Barrel Cortex.
S.-H. Lee, P. W. Land, and D. J. Simons (2007)
J Neurophysiol 97, 4380-4385
   Abstract »    Full Text »    PDF »
Feedback control in active sensing: rat exploratory whisking is modulated by environmental contact.
B. Mitchinson, C. J Martin, R. A Grant, and T. J Prescott (2007)
Proc R Soc B 274, 1035-1041
   Abstract »    Full Text »    PDF »
Ipsilateral Whiskers Suppress Experience-Dependent Plasticity in the Barrel Cortex.
S. Glazewski, B. L. Benedetti, and A. L. Barth (2007)
J. Neurosci. 27, 3910-3920
   Abstract »    Full Text »    PDF »
Facilitating Sensory Responses in Developing Mouse Somatosensory Barrel Cortex.
A. J. Borgdorff, J. F. A. Poulet, and C. C. H. Petersen (2007)
J Neurophysiol 97, 2992-3003
   Abstract »    Full Text »    PDF »
Sensory ecology and perceptual allocation: new prospects for neural networks.
S. M Phelps (2007)
Phil Trans R Soc B 362, 355-367
   Abstract »    Full Text »    PDF »
Sensory Experience Alters Cortical Connectivity and Synaptic Function Site Specifically.
C. E. J. Cheetham, M. S. L. Hammond, C. E. J. Edwards, and G. T. Finnerty (2007)
J. Neurosci. 27, 3456-3465
   Abstract »    Full Text »    PDF »
Modified Sensory Processing in the Barrel Cortex of the Adult Mouse After Chronic Whisker Stimulation.
C. Quairiaux, M. Armstrong-James, and E. Welker (2007)
J Neurophysiol 97, 2130-2147
   Abstract »    Full Text »    PDF »
Brain-Derived Neurotrophic Factor Regulates the Maturation of Layer 4 Fast-Spiking Cells after the Second Postnatal Week in the Developing Barrel Cortex.
C. Itami, F. Kimura, and S. Nakamura (2007)
J. Neurosci. 27, 2241-2252
   Abstract »    Full Text »    PDF »
Spike Timing-Dependent Synaptic Depression in the In Vivo Barrel Cortex of the Rat.
V. Jacob, D. J. Brasier, I. Erchova, D. Feldman, and D. E. Shulz (2007)
J. Neurosci. 27, 1271-1284
   Abstract »    Full Text »    PDF »
Postinfarct Cortical Plasticity and Behavioral Recovery.
R. J. Nudo (2007)
Stroke 38, 840-845
   Abstract »    Full Text »    PDF »
Early Postnatal Plasticity in Neocortex of Fmr1 Knockout Mice.
N. S. Desai, T. M. Casimiro, S. M. Gruber, and P. W. Vanderklish (2006)
J Neurophysiol 96, 1734-1745
   Abstract »    Full Text »    PDF »
Major Effects of Sensory Experiences on the Neocortical Inhibitory Circuits..
Y. Jiao, C. Zhang, Y. Yanagawa, and Q.-Q. Sun (2006)
J. Neurosci. 26, 8691-8701
   Abstract »    Full Text »    PDF »
Plasticity in the nucleus tractus solitarius and its influence on lung and airway reflexes.
A. C. Bonham, C.-Y. Chen, S.-i. Sekizawa, and J. P. Joad (2006)
J Appl Physiol 101, 322-327
   Abstract »    Full Text »    PDF »
Microstimulation of the somatosensory cortex can substitute for vibrissa stimulation during Pavlovian conditioning.
R. Leal-Campanario, J. M. Delgado-Garcia, and A. Gruart (2006)
PNAS 103, 10052-10057
   Abstract »    Full Text »    PDF »
Perceptual learning directs auditory cortical map reorganization through top-down influences..
D. B. Polley, E. E. Steinberg, and M. M. Merzenich (2006)
J. Neurosci. 26, 4970-4982
   Abstract »    Full Text »    PDF »
Synaptic basis for whisker deprivation-induced synaptic depression in rat somatosensory cortex..
K. J. Bender, C. B. Allen, V. A. Bender, and D. E. Feldman (2006)
J. Neurosci. 26, 4155-4165
   Abstract »    Full Text »    PDF »
Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex..
V. A. Bender, K. J. Bender, D. J. Brasier, and D. E. Feldman (2006)
J. Neurosci. 26, 4166-4177
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)