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Science 24 November 2000: Vol. 290. no. 5496, pp. 1536 - 1540 DOI: 10.1126/science.290.5496.1536
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Review
From Micro- to Nanofabrication with Soft Materials
Stephen R. Quake,*
Axel Scherer
Soft materials are finding applications in areas ranging from
microfluidic device technology to nanofabrication. We review recent
work in these areas, discuss the motivation for device fabrication with
soft materials, and describe applications of soft materials. In
particular, we discuss active microfluidic devices for cell sorting and
biochemical assays, replication-molded optics with subdiffraction limit
features, and nanometer-scale resonators and wires formed from
single-molecule DNA templates as examples of how the special properties
of soft materials address outstanding problems in device fabrication.
Department of Applied Physics, MS 128-95, California Institute of
Technology, Pasadena, CA 91125, USA.
*
To whom correspondence should be addressed. E-mail:
quake{at}caltech.edu
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