Science 14 July 1995: Vol. 269. no. 5221, pp. 242 - 244 DOI: 10.1126/science.7618087

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Articles

Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.

A. H. Courtney, E. B. Puffer, J. K. Pontrello, Z.-Q. Yang, and L. L. Kiessling (2009)
PNAS 106, 2500-2505
 |  Abstract »  |  Full Text »  |  PDF »

B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase.

A. Cariappa, H. Takematsu, H. Liu, S. Diaz, K. Haider, C. Boboila, G. Kalloo, M. Connole, H. N. Shi, N. Varki, et al. (2009)
J. Exp. Med. 206, 125-138
 |  Abstract »  |  Full Text »  |  PDF »

Novel Binding Site for Src Homology 2-containing Protein-tyrosine Phosphatase-1 in CD22 Activated by B Lymphocyte Stimulation with Antigen.

C. Zhu, M. Sato, T. Yanagisawa, M. Fujimoto, and T. Tsubata (2008)
J. Biol. Chem. 283, 1653-1659
 |  Abstract »  |  Full Text »  |  PDF »

CD22 Regulates Time Course of Both B Cell Division and Antibody Response.

T. Onodera, J. C. Poe, T. F. Tedder, and T. Tsubata (2008)
J. Immunol. 180, 907-913
 |  Abstract »  |  Full Text »  |  PDF »

Human B-lymphocytes Express {alpha}2-6-Sialylated 6-Sulfo-N-acetyllactosamine Serving as a Preferred Ligand for CD22/Siglec-2.

N. Kimura, K. Ohmori, K. Miyazaki, M. Izawa, Y. Matsuzaki, Y. Yasuda, H. Takematsu, Y. Kozutsumi, A. Moriyama, and R. Kannagi (2007)
J. Biol. Chem. 282, 32200-32207
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Lipid Raft-Targeting Motif in Src Homology 2-Containing Phosphatase 1.

M. Sankarshanan, Z. Ma, T. Iype, and U. Lorenz (2007)
J. Immunol. 179, 483-490
 |  Abstract »  |  Full Text »  |  PDF »

Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors.

K. Horikawa, S. W. Martin, S. L. Pogue, K. Silver, K. Peng, K. Takatsu, and C. C. Goodnow (2007)
J. Exp. Med. 204, 759-769
 |  Abstract »  |  Full Text »  |  PDF »

High-Affinity Ligand Probes of CD22 Overcome the Threshold Set by cis Ligands to Allow for Binding, Endocytosis, and Killing of B Cells..

B. E. Collins, O. Blixt, S. Han, B. Duong, H. Li, J. K. Nathan, N. Bovin, and J. C. Paulson (2006)
J. Immunol. 177, 2994-3003
 |  Abstract »  |  Full Text »  |  PDF »

CD22 Ligand Binding Regulates Normal and Malignant B Lymphocyte Survival In Vivo..

K. M. Haas, S. Sen, I. G. Sanford, A. S. Miller, J. C. Poe, and T. F. Tedder (2006)
J. Immunol. 177, 3063-3073
 |  Abstract »  |  Full Text »  |  PDF »

Sequence Specificity of SHP-1 and SHP-2 Src Homology 2 Domains: CRITICAL ROLES OF RESIDUES BEYOND THE pY+3 POSITION.

D. Imhof, A.-S. Wavreille, A. May, M. Zacharias, S. Tridandapani, and D. Pei (2006)
J. Biol. Chem. 281, 20271-20282
 |  Abstract »  |  Full Text »  |  PDF »

Ig{beta} tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.

A. Gazumyan, A. Reichlin, and M. C. Nussenzweig (2006)
J. Exp. Med. 203, 1785-1794
 |  Abstract »  |  Full Text »  |  PDF »

ST6Gal-I Restrains CD22-Dependent Antigen Receptor Endocytosis and Shp-1 Recruitment in Normal and Pathogenic Immune Signaling..

P. K. Grewal, M. Boton, K. Ramirez, B. E. Collins, A. Saito, R. S. Green, K. Ohtsubo, D. Chui, and J. D. Marth (2006)
Mol. Cell. Biol. 26, 4970-4981
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of B cell development and B cell signalling by CD22 and its ligands {alpha}2,6-linked sialic acids.

S. Ghosh, C. Bandulet, and L. Nitschke (2006)
Int. Immunol. 18, 603-611
 |  Abstract »  |  Full Text »  |  PDF »

RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines.

B. Zhao, S. Maruo, A. Cooper, M. R. Chase, E. Johannsen, E. Kieff, and E. Cahir-McFarland (2006)
PNAS 103, 1900-1905
 |  Abstract »  |  Full Text »  |  PDF »

B Cell Antigen Receptor and CD40 Differentially Regulate CD22 Tyrosine Phosphorylation.

M. Fujimoto, Y. Kuwano, R. Watanabe, N. Asashima, H. Nakashima, S. Yoshitake, H. Okochi, K. Tamaki, J. C. Poe, T. F. Tedder, et al. (2006)
J. Immunol. 176, 873-879
 |  Abstract »  |  Full Text »  |  PDF »

Siglecs--the major subfamily of I-type lectins.

A. Varki and T. Angata (2006)
Glycobiology 16, 1R-27R
 |  Abstract »  |  Full Text »  |  PDF »

Expression of aberrant forms of CD22 on B lymphocytes in Cd22a lupus-prone mice affects ligand binding.

L. Nitschke, F. Lajaunias, T. Moll, L. Ho, E. Martinez-Soria, S. Kikuchi, M.-L. Santiago-Raber, C. Dix, R. M. E. Parkhouse, and S. Izui (2006)
Int. Immunol. 18, 59-68
 |  Abstract »  |  Full Text »  |  PDF »

Complement Component C3d-Antigen Complexes Can Either Augment or Inhibit B Lymphocyte Activation and Humoral Immunity in Mice Depending on the Degree of CD21/CD19 Complex Engagement.

Y. Lee, K. M. Haas, D. O. Gor, X. Ding, D. R. Karp, N. S. Greenspan, J. C. Poe, and T. F. Tedder (2005)
J. Immunol. 175, 8011-8023
 |  Abstract »  |  Full Text »  |  PDF »

Cell surface sialic acids do not affect primary CD22 interactions with CD45 and surface IgM nor the rate of constitutive CD22 endocytosis.

M. Zhang and A. Varki (2004)
Glycobiology 14, 939-949
 |  Abstract »  |  Full Text »  |  PDF »

Differential B cell expression of mouse Fc receptor homologs.

R. S. Davis, R. P. Stephan, C.-C. Chen, G. Dennis Jr., and M. D. Cooper (2004)
Int. Immunol. 16, 1343-1353
 |  Abstract »  |  Full Text »  |  PDF »

Impairment of B cell receptor-mediated Ca2+ influx, activation of mitogen-activated protein kinases and growth inhibition in CD72-deficient BAL-17 cells.

M. Ogimoto, G. Ichinowatari, N. Watanabe, N. Tada, K. Mizuno, and H. Yakura (2004)
Int. Immunol. 16, 971-982
 |  Abstract »  |  Full Text »  |  PDF »

Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact.

B. E. Collins, O. Blixt, A. R. DeSieno, N. Bovin, J. D. Marth, and J. C. Paulson (2004)
PNAS 101, 6104-6109
 |  Abstract »  |  Full Text »  |  PDF »

Severely Impaired B Lymphocyte Proliferation, Survival, and Induction of the c-Myc:Cullin 1 Ubiquitin Ligase Pathway Resulting from CD22 Deficiency on the C57BL/6 Genetic Background.

J. C. Poe, K. M. Haas, J. Uchida, Y. Lee, M. Fujimoto, and T. F. Tedder (2004)
J. Immunol. 172, 2100-2110
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Transitional and marginal zone B cells have a high proportion of unmasked CD22: implications for BCR signaling.

C.-P. Danzer, B. E. Collins, O. Blixt, J. C. Paulson, and L. Nitschke (2003)
Int. Immunol. 15, 1137-1147
 |  Abstract »  |  Full Text »  |  PDF »

Epratuzumab, a Humanized Monoclonal Antibody Targeting CD22: Characterization of in Vitro Properties.

J. Carnahan, P. Wang, R. Kendall, C. Chen, S. Hu, T. Boone, T. Juan, J. Talvenheimo, S. Montestruque, J. Sun, et al. (2003)
Clin. Cancer Res. 9, 3982s-3990s
 |  Abstract »  |  Full Text »

Inhibitory Coreceptors Activated by Antigens But Not by Anti-Ig Heavy Chain Antibodies Install Requirement of Costimulation Through CD40 for Survival and Proliferation of B Cells.

Y. Hokazono, T. Adachi, M. Wabl, N. Tada, T. Amagasa, and T. Tsubata (2003)
J. Immunol. 171, 1835-1843
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The B Cell Coreceptor CD22 Associates with AP50, a Clathrin-Coated Pit Adapter Protein, Via Tyrosine-Dependent Interaction.

B. John, B. R. Herrin, C. Raman, Y.-n. Wang, K. R. Bobbitt, B. A. Brody, and L. B. Justement (2003)
J. Immunol. 170, 3534-3543
 |  Abstract »  |  Full Text »  |  PDF »

A Distinct Signaling Pathway Used by the IgG-Containing B Cell Antigen Receptor.

C. Wakabayashi, T. Adachi, J. Wienands, and T. Tsubata (2002)
Science 298, 2392-2395
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The Activation and Subsequent Regulatory Roles of Lyn and CD19 After B Cell Receptor Ligation are Independent.

Y. Xu, S.-J. E. Beavitt, K. W. Harder, M. L. Hibbs, and D. M. Tarlinton (2002)
J. Immunol. 169, 6910-6918
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Second Type of Human beta -Galactoside alpha 2,6-Sialyltransferase (ST6Gal II), Which Sialylates Galbeta 1,4GlcNAc Structures on Oligosaccharides Preferentially. GENOMIC ANALYSIS OF HUMAN SIALYLTRANSFERASE GENES.

S. Takashima, S. Tsuji, and M. Tsujimoto (2002)
J. Biol. Chem. 277, 45719-45728
 |  Abstract »  |  Full Text »  |  PDF »

Constitutively unmasked CD22 on B cells of ST6Gal I knockout mice: novel sialoside probe for murine CD22.

B. E. Collins, O. Blixt, N. V. Bovin, C.-P. Danzer, D. Chui, J. D. Marth, L. Nitschke, and J. C. Paulson (2002)
Glycobiology 12, 563-571
 |  Abstract »  |  Full Text »  |  PDF »

Complement's participation in acquired immunity.

C. H. Nielsen and R. G. Q. Leslie (2002)
J. Leukoc. Biol. 72, 249-261
 |  Abstract »  |  Full Text »  |  PDF »

Src Homology Region 2 Domain-Containing Phosphatase 1 Positively Regulates B Cell Receptor-Induced Apoptosis by Modulating Association of B Cell Linker Protein with Nck and Activation of c-Jun NH2-Terminal Kinase.

K. Mizuno, Y. Tagawa, K. Mitomo, N. Watanabe, T. Katagiri, M. Ogimoto, and H. Yakura (2002)
J. Immunol. 169, 778-786
 |  Abstract »  |  Full Text »  |  PDF »

Differentially Regulated Expression and Function of CD22 in Activated B-1 and B-2 Lymphocytes.

F. Lajaunias, L. Nitschke, T. Moll, E. Martinez-Soria, I. Semac, Y. Chicheportiche, R. M. E. Parkhouse, and S. Izui (2002)
J. Immunol. 168, 6078-6083
 |  Abstract »  |  Full Text »  |  PDF »

The variable, CH1, CH2 and CH3 domains of Ig heavy chain are dispensable for pre-BCR function in transgenic mice.

S. A. Muljo and M. S. Schlissel (2002)
Int. Immunol. 14, 577-584
 |  Abstract »  |  Full Text »  |  PDF »

IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.

I. Miller, G. Hatzivassiliou, G. Cattoretti, C. Mendelsohn, and R. Dalla-Favera (2002)
Blood 99, 2662-2669
 |  Abstract »  |  Full Text »  |  PDF »

Visualization of Negative Signaling in B Cells by Quantitative Confocal Microscopy.

H. Phee, W. Rodgers, and K. M. Coggeshall (2001)
Mol. Cell. Biol. 21, 8615-8625
 |  Abstract »  |  Full Text »  |  PDF »

Immunoreceptor Tyrosine-Based Inhibitory Motif of the IL-4 Receptor Associates with SH2-Containing Phosphatases and Regulates IL-4-Induced Proliferation.

M. Kashiwada, C. C. Giallourakis, P.-Y. Pan, and P. B. Rothman (2001)
J. Immunol. 167, 6382-6387
 |  Abstract »  |  Full Text »  |  PDF »

The Carboxyl Terminus of the Granulocyte Colony- Stimulating Factor Receptor, Truncated in Patients with Severe Congenital Neutropenia/Acute Myeloid Leukemia, Is Required for SH2-Containing Phosphatase-1 Suppression of Stat Activation.

F. Dong, Y. Qiu, T. Yi, I. P. Touw, and A. C. Larner (2001)
J. Immunol. 167, 6447-6452
 |  Abstract »  |  Full Text »  |  PDF »

CD22 Regulates B Cell Receptor-mediated Signals via Two Domains That Independently Recruit Grb2 and SHP-1.

K. L. Otipoby, K. E. Draves, and E. A. Clark (2001)
J. Biol. Chem. 276, 44315-44322
 |  Abstract »  |  Full Text »  |  PDF »

B cell receptor signaling and autoimmunity.

P. HASLER and M. ZOUALI (2001)
FASEB J 15, 2085-2098
 |  Abstract »  |  Full Text »  |  PDF »

Positive Signaling Through CD72 Induces Mitogen-Activated Protein Kinase Activation and Synergizes with B Cell Receptor Signals to Induce X-Linked Immunodeficiency B Cell Proliferation.

H.-J. Wu, C. Venkataraman, S. Estus, C. Dong, R. J. Davis, R. A. Flavell, and S. Bondada (2001)
J. Immunol. 167, 1263-1273
 |  Abstract »  |  Full Text »  |  PDF »

Development and Maintenance of a B220- Memory B Cell Compartment.

D. J. Driver, L. J. McHeyzer-Williams, M. Cool, D. B. Stetson, and M. G. McHeyzer-Williams (2001)
J. Immunol. 167, 1393-1405
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1.

J.-F. Fortin, B. Barbeau, G. A. Robichaud, M.-E. Pare, A.-M. Lemieux, and M. J. Tremblay (2001)
Blood 97, 2390-2400
 |  Abstract »  |  Full Text »  |  PDF »

Antigen Receptor Proximal Signaling in Splenic B-2 Cell Subsets.

X. Li, F. Martin, A. M. Oliver, J. F. Kearney, and R. H. Carter (2001)
J. Immunol. 166, 3122-3129
 |  Abstract »  |  Full Text »  |  PDF »

CD5 Is Dissociated from the B-Cell Receptor in B Cells from Bovine Leukemia Virus-Infected, Persistently Lymphocytotic Cattle: Consequences to B-Cell Receptor-Mediated Apoptosis.

G. H. Cantor, S. M. Pritchard, F. Dequiedt, L. Willems, R. Kettmann, and W. C. Davis (2001)
J. Virol. 75, 1689-1696
 |  Abstract »  |  Full Text »

Lupus-Specific Antiribonucleoprotein B Cell Tolerance in Nonautoimmune Mice Is Maintained by Differentiation to B-1 and Governed by B Cell Receptor Signaling Thresholds.

Y. Qian, C. Santiago, M. Borrero, T. F. Tedder, and S. H. Clarke (2001)
J. Immunol. 166, 2412-2419
 |  Abstract »  |  Full Text »  |  PDF »

Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway.

L. S. Quek, J.-M. Pasquet, I. Hers, R. Cornall, G. Knight, M. Barnes, M. L. Hibbs, A. R. Dunn, C. A. Lowell, and S. P. Watson (2000)
Blood 96, 4246-4253
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of MHC Class II Signal Transduction by the B Cell Coreceptors CD19 and CD22.

K. R. Bobbitt and L. B. Justement (2000)
J. Immunol. 165, 5588-5596
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of Src Homology 2-Containing Phosphatase 1 Results in Abnormalities in Murine Neutrophil Function: Studies in Motheaten Mice.

J. Kruger, J. R. Butler, V. Cherapanov, Q. Dong, H. Ginzberg, A. Govindarajan, S. Grinstein, K. A. Siminovitch, and G. P. Downey (2000)
J. Immunol. 165, 5847-5859
 |  Abstract »  |  Full Text »  |  PDF »

Src Homology Region 2 (SH2) Domain-Containing Phosphatase-1 Dephosphorylates B Cell Linker Protein/SH2 Domain Leukocyte Protein of 65 kDa and Selectively Regulates c-Jun NH2-Terminal Kinase Activation in B Cells.

K. Mizuno, Y. Tagawa, K. Mitomo, Y. Arimura, N. Hatano, T. Katagiri, M. Ogimoto, and H. Yakura (2000)
J. Immunol. 165, 1344-1351
 |  Abstract »  |  Full Text »  |  PDF »

Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

S. P. Paul, L. S. Taylor, E. K. Stansbury, and D. W. McVicar (2000)
Blood 96, 483-490
 |  Abstract »  |  Full Text »  |  PDF »

New Aspects of Siglec Binding Specificities, Including the Significance of Fucosylation and of the Sialyl-Tn Epitope.

E. C. M. Brinkman-Van der Linden and A. Varki (2000)
J. Biol. Chem. 275, 8625-8632
 |  Abstract »  |  Full Text »  |  PDF »

Loss of N-Glycolylneuraminic Acid in Human Evolution. IMPLICATIONS FOR SIALIC ACID RECOGNITION BY SIGLECS.

E. C. M. Brinkman-Van der Linden, E. R. Sjoberg, L. R. Juneja, P. R. Crocker, N. Varki, and A. Varki (2000)
J. Biol. Chem. 275, 8633-8640
 |  Abstract »  |  Full Text »  |  PDF »

Systematic Analysis of the Role of CD19 Cytoplasmic Tyrosines in Enhancement of Activation in Daudi Human B Cells: Clustering of Phospholipase C and Vav and of Grb2 and Sos with Different CD19 Tyrosines.

S. R. Brooks, X. Li, E. J. Volanakis, and R. H. Carter (2000)
J. Immunol. 164, 3123-3131
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory and Signaling Properties of the Vav Family.

X. R. Bustelo (2000)
Mol. Cell. Biol. 20, 1461-1477
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PILRalpha , a Novel Immunoreceptor Tyrosine-based Inhibitory Motif-bearing Protein, Recruits SHP-1 upon Tyrosine Phosphorylation and Is Paired with the Truncated Counterpart PILRbeta.

D. D. Mousseau, D. Banville, D. L'Abbe, P. Bouchard, and S.-H. Shen (2000)
J. Biol. Chem. 275, 4467-4474
 |  Abstract »  |  Full Text »  |  PDF »

CD72 Negatively Regulates Signaling Through the Antigen Receptor of B Cells.

T. Adachi, C. Wakabayashi, T. Nakayama, H. Yakura, and T. Tsubata (2000)
J. Immunol. 164, 1223-1229
 |  Abstract »  |  Full Text »  |  PDF »

Positive Regulation of c-Jun N-Terminal Kinase and TNF-{alpha} Production But Not Histamine Release by SHP-1 in RBL-2H3 Mast Cells.

Z.-H. Xie, J. Zhang, and R. P. Siraganian (2000)
J. Immunol. 164, 1521-1528
 |  Abstract »  |  Full Text »  |  PDF »

The Pseudo-immunoreceptor Tyrosine-based Activation Motif of CD5 Mediates Its Inhibitory Action on B-cell Receptor Signaling.

H. Gary-Gouy, P. Bruhns, C. Schmitt, A. Dalloul, M. Daeron, and G. Bismuth (2000)
J. Biol. Chem. 275, 548-556
 |  Abstract »  |  Full Text »  |  PDF »

Stimulatory Function of Paired Immunoglobulin-like Receptor-A in Mast Cell Line by Associating with Subunits Common to Fc Receptors.

M. Ono, T. Yuasa, C. Ra, and T. Takai (1999)
J. Biol. Chem. 274, 30288-30296
 |  Abstract »  |  Full Text »  |  PDF »

Human 70-kDa SHP-1L Differs from 68-kDa SHP-1 in Its C-terminal Structure and Catalytic Activity.

Y.-J. Jin, C.-L. Yu, and S. J. Burakoff (1999)
J. Biol. Chem. 274, 28301-28307
 |  Abstract »  |  Full Text »  |  PDF »

Human 70-kDa SHP-1L Differs from 68-kDa SHP-1 in Its C-terminal Structure and Catalytic Activity.

Y.-J. Jin, C.-L. Yu, and S. J. Burakoff (1999)
J. Biol. Chem. 274, 99999
 |  Abstract »  |  Full Text »

Involvement of the SHP-1 Tyrosine Phosphatase in Regulation of T Cell Selection.

J. Zhang, A.-K. Somani, D. Yuen, Y. Yang, P. E. Love, and K. A. Siminovitch (1999)
J. Immunol. 163, 3012-3021
 |  Abstract »  |  Full Text »  |  PDF »

CD22 Cross-Linking Generates B-Cell Antigen Receptor-Independent Signals That Activate the JNK/SAPK Signaling Cascade.

J. M. Tuscano, A. Riva, S. N. Toscano, T. F. Tedder, and J. H. Kehrl (1999)
Blood 94, 1382-1392
 |  Abstract »  |  Full Text »  |  PDF »

OB-BP1/Siglec-6. A LEPTIN- AND SIALIC ACID-BINDING PROTEIN OF THE IMMUNOGLOBULIN SUPERFAMILY.

N. Patel, E. C. M. B.-V. d. Linden, S. W. Altmann, K. Gish, S. Balasubramanian, J. C. Timans, D. Peterson, M. P. Bell, J. F. Bazan, A. Varki, et al. (1999)
J. Biol. Chem. 274, 22729-22738
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Tyrosine Phosphorylation-dependent Interactions between Stimulatory Effector Proteins and the B Cell Co-receptor CD22.

J. Yohannan, J. Wienands, K. M. Coggeshall, and L. B. Justement (1999)
J. Biol. Chem. 274, 18769-18776
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Human 2B4, an Activating NK Cell Receptor, Recruits the Protein Tyrosine Phosphatase SHP-2 and the Adaptor Signaling Protein SAP.

S. G. Tangye, S. Lazetic, E. Woollatt, G. R. Sutherland, L. L. Lanier, and J. H. Phillips (1999)
J. Immunol. 162, 6981-6985
 |  Abstract »  |  Full Text »  |  PDF »

The Src-Homology Domain 2-Bearing Protein Tyrosine Phosphatase-1 Inhibits Antigen Receptor-Induced Apoptosis of Activated Peripheral T Cells.

J. Zhang, A.-K. Somani, S. Watt, G. B. Mills, and K. A. Siminovitch (1999)
J. Immunol. 162, 6359-6367
 |  Abstract »  |  Full Text »  |  PDF »

Identification of CD22 Ligands on Bone Marrow Sinusoidal Endothelium Implicated in CD22-dependent Homing of Recirculating B Cells.

L. Nitschke, H. Floyd, D. J.P. Ferguson, and P. R. Crocker (1999)
J. Exp. Med. 189, 1513-1518
 |  Abstract »  |  Full Text »  |  PDF »

CD45 Regulates Tyrosine Phosphorylation of CD22 and Its Association with the Protein Tyrosine Phosphatase SHP-1.

S. F. Greer and L. B. Justement (1999)
J. Immunol. 162, 5278-5286
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency in CD22, a B Cell-specific Inhibitory Receptor, Is Sufficient to Predispose to Development of High Affinity Autoantibodies.

T. L. O'Keefe, G. T. Williams, F. D. Batista, and M. S. Neuberger (1999)
J. Exp. Med. 189, 1307-1313
 |  Abstract »  |  Full Text »  |  PDF »

CD5 Negatively Regulates the T-Cell Antigen Receptor Signal Transduction Pathway: Involvement of SH2-Containing Phosphotyrosine Phosphatase SHP-1.

J. J. Perez-Villar, G. S. Whitney, M. A. Bowen, D. H. Hewgill, A. A. Aruffo, and S. B. Kanner (1999)
Mol. Cell. Biol. 19, 2903-2912
 |  Abstract »  |  Full Text »  |  PDF »

TCR Signaling Thresholds Regulating T Cell Development and Activation Are Dependent upon SHP-1.

K. G. Johnson, F. G. LeRoy, L. K. Borysiewicz, and R. J. Matthews (1999)
J. Immunol. 162, 3802-3813
 |  Abstract »  |  Full Text »  |  PDF »

Negative Regulation of Myeloid Cell Proliferation and Function by the SH2 Domain-Containing Tyrosine Phosphatase-1.

Q. Dong, K. A. Siminovitch, L. Fialkow, T. Fukushima, and G. P. Downey (1999)
J. Immunol. 162, 3220-3230
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Dominant-Negative Src-Homology Domain 2-Containing Protein Tyrosine Phosphatase-1 Results in Increased Syk Tyrosine Kinase Activity and B Cell Activation.

L. B. Dustin, D. R. Plas, J. Wong, Y. T. Hu, C. Soto, A. C. Chan, and M. L. Thomas (1999)
J. Immunol. 162, 2717-2724
 |  Abstract »  |  Full Text »  |  PDF »

Specificity of the SH2 Domains of SHP-1 in the Interaction with the Immunoreceptor Tyrosine-Based Inhibitory Motif-Bearing Receptor gp49B.

L. L. Wang, J. Blasioli, D. R. Plas, M. L. Thomas, and W. M. Yokoyama (1999)
J. Immunol. 162, 1318-1323
 |  Abstract »  |  Full Text »  |  PDF »

Definition of the Sites of Interaction between the Protein Tyrosine Phosphatase SHP-1 and CD22.

J. Blasioli, S. Paust, and M. L. Thomas (1999)
J. Biol. Chem. 274, 2303-2307
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Inhibitory Receptors and Their Modes of Action.

D.C. FONG and J.C. CAMBIER (1999)
Cold Spring Harb Symp Quant Biol 64, 329-334
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The Carboxyl-terminal Region of Biliary Glycoprotein Controls Its Tyrosine Phosphorylation and Association with Protein-tyrosine Phosphatases SHP-1 and SHP-2 in Epithelial Cells.

M. Huber, L. Izzi, P. Grondin, C. Houde, T. Kunath, A. Veillette, and N. Beauchemin (1999)
J. Biol. Chem. 274, 335-344
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Internalization of the Lymphocytic Surface Protein CD22 Is Controlled by a Novel Membrane Proximal Cytoplasmic Motif.

C. H. T. Chan, J. Wang, R. R. French, and M. J. Glennie (1998)
J. Biol. Chem. 273, 27809-27815
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Recruitment and Activation of SHP-1 Protein-tyrosine Phosphatase by Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1). IDENTIFICATION OF IMMUNORECEPTOR TYROSINE-BASED INHIBITORY MOTIF-LIKE BINDING MOTIFS AND SUBSTRATES.

C. T. Hua, J. R. Gamble, M. A. Vadas, and D. E. Jackson (1998)
J. Biol. Chem. 273, 28332-28340
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SLP-76 Is a Direct Substrate of SHP-1 Recruited to Killer Cell Inhibitory Receptors.

B. A. Binstadt, D. D. Billadeau, B. L. Williams, N. Fang, T. Yi, G. A. Koretzky, R. T. Abraham, and P. J. Leibson (1998)
J. Biol. Chem. 273, 27518-27523
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Cutting Edge: The B Cell Surface Protein CD72 Recruits the Tyrosine Phosphatase SHP-1 upon Tyrosine Phosphorylation.

T. Adachi, H. Flaswinkel, H. Yakura, M. Reth, and T. Tsubata (1998)
J. Immunol. 160, 4662-4665
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SHP-1 Phosphatase C-Terminus Interacts With Novel Substrates p32/p30 During Erythropoietin and Interleukin-3 Mitogenic Responses.

W. Yang, M. Tabrizi, K. Berrada, and T. Yi (1998)
Blood 91, 3746-3755
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A Double-Edged Kinase Lyn: A Positive and Negative Regulator for Antigen Receptor-mediated Signals.

H. Nishizumi, K. Horikawa, I. Mlinaric-Rascan, and T. Yamamoto (1998)
J. Exp. Med. 187, 1343-1348
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Roles of the Complex Formation of SHPS-1 with SHP-2 in Insulin-stimulated Mitogen-activated Protein Kinase Activation.

T. Takada, T. Matozaki, H. Takeda, K. Fukunaga, T. Noguchi, Y. Fujioka, I. Okazaki, M. Tsuda, T. Yamao, F. Ochi, et al. (1998)
J. Biol. Chem. 273, 9234-9242
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SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain.

M. Kozlowski, L. Larose, F. Lee, D. M. Le, R. Rottapel, and K. A. Siminovitch (1998)
Mol. Cell. Biol. 18, 2089-2099
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Spontaneous Follicular Exclusion of SHP1-deficient B Cells Is Conditional on the Presence of Competitor Wild-type B Cells.

K. N. Schmidt, C. W. Hsu, C. T. Griffin, C. C. Goodnow, and J. G. Cyster (1998)
J. Exp. Med. 187, 929-937
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Inhibition of the B Cell by CD22: A Requirement for Lyn.

K. G.C. Smith, D. M. Tarlinton, G. M. Doody, M. L. Hibbs, and D. T. Fearon (1998)
J. Exp. Med. 187, 807-811
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Cutting Edge: Lyn-Mediated Down-Regulation of B Cell Antigen Receptor Signaling: Inhibition of Protein Kinase C Activation by Lyn in a Kinase-Independent Fashion.

H. Katsuta, S. Tsuji, Y. Niho, T. Kurosaki, and D. Kitamura (1998)
J. Immunol. 160, 1547-1551
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Association of Tyrosine Phosphatases SHP-1 and SHP-2, Inositol 5-Phosphatase SHIP with gp49B1, and Chromosomal Assignment of the Gene.

A. Kuroiwa, Y. Yamashita, M. Inui, T. Yuasa, M. Ono, A. Nagabukuro, Y. Matsuda, and T. Takai (1998)
J. Biol. Chem. 273, 1070-1074
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The Protein-tyrosine Phosphatase SHP-2 Associates with Tyrosine-phosphorylated Adhesion Molecule PECAM-1 (CD31).

K. Sagawa, T. Kimura, M. Swieter, and R. P. Siraganian (1997)
J. Biol. Chem. 272, 31086-31091
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What Goes Up Must Come Down: The Emerging Spectrum of Inhibitory Receptors.

W. M. Yokoyama (1997)
J. Exp. Med. 186, 1803-1808
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Btk dosage determines sensitivity to B cell antigen receptor cross-linking.

A. B. Satterthwaite, H. Cheroutre, W. N. Khan, P. Sideras, and O. N. Witte (1997)
PNAS 94, 13152-13157
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CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling.

S. Sato, P. J. Jansen, and T. F. Tedder (1997)
PNAS 94, 13158-13162
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Downregulated Expression of SHP-1 in Burkitt Lymphomas and Germinal Center B Lymphocytes.

C. C. Delibrias, J. E. Floettmann, M. Rowe, and D. T. Fearon (1997)
J. Exp. Med. 186, 1575-1583
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