Science 1 January 1993: Vol. 259. no. 5091, pp. 87 - 91 DOI: 10.1126/science.7678183

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Articles

Lower Zinc-{alpha}2-Glycoprotein Production by Adipose Tissue and Liver in Obese Patients Unrelated to Insulin Resistance.

D. M. Selva, A. Lecube, C. Hernandez, J. A. Baena, J. M. Fort, and R. Simo (2009)
J. Clin. Endocrinol. Metab. 94, 4499-4507
 |  Abstract »  |  Full Text »  |  PDF »

Changes in Hypothalamically Mediated Acute-Phase Inflammatory Responses to Lipopolysaccharide in Diet-Induced Obese Rats.

J. Pohl, B. Woodside, and G. N. Luheshi (2009)
Endocrinology 150, 4901-4910
 |  Abstract »  |  Full Text »  |  PDF »

Short-Term Regulation of Tumor Necrosis Factor-{alpha}-Induced Lipolysis in 3T3-L1 Adipocytes Is Mediated through the Inducible Nitric Oxide Synthase/Nitric Oxide-Dependent Pathway.

C.-C. Lien, L.-C. Au, Y.-L. Tsai, L.-T. Ho, and C.-C. Juan (2009)
Endocrinology 150, 4892-4900
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle.

E.-G. Hong, H. J. Ko, Y.-R. Cho, H.-J. Kim, Z. Ma, T. Y. Yu, R. H. Friedline, E. Kurt-Jones, R. Finberg, M. A. Fischer, et al. (2009)
Diabetes 58, 2525-2535
 |  Abstract »  |  Full Text »  |  PDF »

Nutrient Stress Activates Inflammation and Reduces Glucose Metabolism by Suppressing AMP-Activated Protein Kinase in the Heart.

H. J. Ko, Z. Zhang, D. Y. Jung, J. Y. Jun, Z. Ma, K. E. Jones, S. Y. Chan, and J. K. Kim (2009)
Diabetes 58, 2536-2546
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the NH2-Terminal Fragment of RasGAP in Pancreatic {beta}-Cells Increases Their Resistance to Stresses and Protects Mice From Diabetes.

J.-Y. Yang, J. Walicki, E. Jaccard, G. Dubuis, N. Bulat, J.-P. Hornung, B. Thorens, and C. Widmann (2009)
Diabetes 58, 2596-2606
 |  Abstract »  |  Full Text »  |  PDF »

Adipocytes as Immune Cells: Differential Expression of TWEAK, BAFF, and APRIL and Their Receptors (Fn14, BAFF-R, TACI, and BCMA) at Different Stages of Normal and Pathological Adipose Tissue Development.

V.-I. Alexaki, G. Notas, V. Pelekanou, M. Kampa, M. Valkanou, P. Theodoropoulos, E. N. Stathopoulos, A. Tsapis, and E. Castanas (2009)
J. Immunol. 183, 5948-5956
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Tumor Necrosis Factor-{alpha} Does Not Mediate Diabetes-Induced Vascular Inflammation in Mice.

J. Nilsson-Ohman, G. N. Fredrikson, L. M. Nilsson-Berglund, C. Gustavsson, E. Bengtsson, M.-L. Smith, C.-D. Agardh, E. Agardh, S. Jovinge, M. F. Gomez, et al. (2009)
Arterioscler Thromb Vasc Biol 29, 1465-1470
 |  Abstract »  |  Full Text »  |  PDF »

Role of MCP-1 in tumor necrosis factor-{alpha}-induced endothelial dysfunction in type 2 diabetic mice.

J. Yang, Y. Park, H. Zhang, X. Gao, E. Wilson, W. Zimmer, L. Abbott, and C. Zhang (2009)
Am J Physiol Heart Circ Physiol 297, H1208-H1216
 |  Abstract »  |  Full Text »  |  PDF »

AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death.

G. Kewalramani, P. Puthanveetil, F. Wang, M. S. Kim, S. Deppe, A. Abrahani, D. S. Luciani, J. D. Johnson, and B. Rodrigues (2009)
Cardiovasc Res 84, 42-53
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Insights and Therapeutic Targets for Diabetic Endothelial Dysfunction.

J. Xu and M.-H. Zou (2009)
Circulation 120, 1266-1286
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Peroxisome Proliferator-activated Receptor {gamma} Regulates Expression of the Anti-lipolytic G-protein-coupled Receptor 81 (GPR81/Gpr81).

E. H. Jeninga, A. Bugge, R. Nielsen, S. Kersten, N. Hamers, C. Dani, M. Wabitsch, R. Berger, H. G. Stunnenberg, S. Mandrup, et al. (2009)
J. Biol. Chem. 284, 26385-26393
 |  Abstract »  |  Full Text »  |  PDF »

c-Jun N-Terminal Kinase 1/2 Activation by Tumor Necrosis Factor-{alpha} Induces Insulin Resistance In Human Visceral But Not Subcutaneous Adipocytes: Reversal by Liver X Receptor Agonists.

S. Fernandez-Veledo, R. Vila-Bedmar, I. Nieto-Vazquez, and M. Lorenzo (2009)
J. Clin. Endocrinol. Metab. 94, 3583-3593
 |  Abstract »  |  Full Text »  |  PDF »

Receptors for Tumor Necrosis Factor-{alpha} Play a Protective Role against Obesity and Alter Adipose Tissue Macrophage Status.

N. Pamir, T. S. McMillen, K. J. Kaiyala, M. W. Schwartz, and R. C. LeBoeuf (2009)
Endocrinology 150, 4124-4134
 |  Abstract »  |  Full Text »  |  PDF »

Hypoxia-Inducible Factor 1{alpha} Induces Fibrosis and Insulin Resistance in White Adipose Tissue.

N. Halberg, T. Khan, M. E. Trujillo, I. Wernstedt-Asterholm, A. D. Attie, S. Sherwani, Z. V. Wang, S. Landskroner-Eiger, S. Dineen, U. J. Magalang, et al. (2009)
Mol. Cell. Biol. 29, 4467-4483
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Homocysteine-Lowering Treatment With Folic Acid and B Vitamins on Risk of Type 2 Diabetes in Women: A Randomized, Controlled Trial.

Y. Song, N. R. Cook, C. M. Albert, M. Van Denburgh, and J. E. Manson (2009)
Diabetes 58, 1921-1928
 |  Abstract »  |  Full Text »  |  PDF »

Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats.

K. S. C. Gollisch, J. Brandauer, N. Jessen, T. Toyoda, A. Nayer, M. F. Hirshman, and L. J. Goodyear (2009)
Am J Physiol Endocrinol Metab 297, E495-E504
 |  Abstract »  |  Full Text »  |  PDF »

The effect of interleukin-6 and the interleukin-6 receptor on glucose transport in mouse skeletal muscle.

S. R. Gray, A. Ratkevicius, H. Wackerhage, P. Coats, and M. A. Nimmo (2009)
Exp Physiol 94, 899-905
 |  Abstract »  |  Full Text »  |  PDF »

The Impact of Body Mass Index on Mortality After Stroke.

A. Towfighi and B. Ovbiagele (2009)
Stroke 40, 2704-2708
 |  Abstract »  |  Full Text »  |  PDF »

Adipokines in the skeleton: influence on cartilage function and joint degenerative diseases.

R. Gomez, F. Lago, J. Gomez-Reino, C. Dieguez, and O. Gualillo (2009)
J. Mol. Endocrinol. 43, 11-18
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A new mouse model of metabolic syndrome and associated complications.

Y. Wang, Y. Zheng, P. M Nishina, and J. K Naggert (2009)
J. Endocrinol. 202, 17-28
 |  Abstract »  |  Full Text »  |  PDF »

Adiposity and insulin resistance in nondiabetic hemodialysis patients: effects of high energy supplementation.

S.-C. Hung and D.-C. Tarng (2009)
Am. J. Clinical Nutrition 90, 64-69
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial Dynamics in Mammalian Health and Disease.

M. Liesa, M. Palacin, and A. Zorzano (2009)
Physiol Rev 89, 799-845
 |  Abstract »  |  Full Text »  |  PDF »

Reduced Adiposity and High-Fat Diet-Induced Adipose Inflammation in Mice Deficient for Phosphodiesterase 4B.

R. Zhang, E. Maratos-Flier, and J. S. Flier (2009)
Endocrinology 150, 3076-3082
 |  Abstract »  |  Full Text »  |  PDF »

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome.

G. Yang, L. Badeanlou, J. Bielawski, A. J. Roberts, Y. A. Hannun, and F. Samad (2009)
Am J Physiol Endocrinol Metab 297, E211-E224
 |  Abstract »  |  Full Text »  |  PDF »

Genetic locus on rat chromosome 20 regulates diet-induced adipocyte hypertrophy: a microarray gene expression study.

C. Bourdon, S. Hojna, M. Jordan, J. Berube, V. Kren, M. Pravenec, P. Liu, S. Arab, and Z. Pausova (2009)
Physiol Genomics 38, 63-72
 |  Abstract »  |  Full Text »  |  PDF »

The Relation of Genetic and Environmental Factors to Systemic Inflammatory Biomarker Concentrations.

R. B. Schnabel, K. L. Lunetta, M. G. Larson, J. Dupuis, I. Lipinska, J. Rong, M.-H. Chen, Z. Zhao, J. F. Yamamoto, J. B. Meigs, et al. (2009)
Circ Cardiovasc Genet 2, 229-237
 |  Abstract »  |  Full Text »  |  PDF »

Getting the message across: mechanisms of physiological cross talk by adipose tissue.

D.-E. Lee, S. Kehlenbrink, H. Lee, M. Hawkins, and J. S. Yudkin (2009)
Am J Physiol Endocrinol Metab 296, E1210-E1229
 |  Abstract »  |  Full Text »  |  PDF »

Xanthones from Mangosteen Prevent Lipopolysaccharide-Mediated Inflammation and Insulin Resistance in Primary Cultures of Human Adipocytes.

A. Bumrungpert, R. W. Kalpravidh, C. Chitchumroonchokchai, C.-C. Chuang, T. West, A. Kennedy, and M. McIntosh (2009)
J. Nutr. 139, 1185-1191
 |  Abstract »  |  Full Text »  |  PDF »

Joint effect of obesity and TNFA variability on asthma: two international cohort studies.

F. Castro-Giner, M. Kogevinas, M. Imboden, R. de Cid, D. Jarvis, M. Machler, W. Berger, P. Burney, K. A. Franklin, J. R. Gonzalez, et al. (2009)
Eur. Respir. J. 33, 1003-1009
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of GPR40 in Pancreatic {beta}-Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice.

K. Nagasumi, R. Esaki, K. Iwachidow, Y. Yasuhara, K. Ogi, H. Tanaka, M. Nakata, T. Yano, K. Shimakawa, S. Taketomi, et al. (2009)
Diabetes 58, 1067-1076
 |  Abstract »  |  Full Text »  |  PDF »

Growth hormone, menopause and ageing: no definite evidence for 'rejuvenation' with growth hormone.

G. Fanciulli, A. Delitala, and G. Delitala (2009)
Hum. Reprod. Update 15, 341-358
 |  Abstract »  |  Full Text »  |  PDF »

Relation of Abdominal Fat Depots to Systemic Markers of Inflammation in Type 2 Diabetes.

S. Sam, S. Haffner, M. H. Davidson, R. B. D'Agostino Sr., S. Feinstein, G. Kondos, A. Perez, and T. Mazzone (2009)
Diabetes Care 32, 932-937
 |  Abstract »  |  Full Text »  |  PDF »

A Dual Role of CD4+ T Cells in Adipose Tissue?.

C. M. Matter and M. A. S. Stein (2009)
Circ. Res. 104, 928-930
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Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation.

M. V. Chakravarthy, Y. Zhu, L. Yin, T. Coleman, K. L. Pappan, C. A. Marshall, M. L. McDaniel, and C. F. Semenkovich (2009)
J. Lipid Res. 50, 630-640
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Cancer Cachexia.

M. J. Tisdale (2009)
Physiol Rev 89, 381-410
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of IRS proteins, insulin action, and insulin resistance.

S. Boura-Halfon and Y. Zick (2009)
Am J Physiol Endocrinol Metab 296, E581-E591
 |  Abstract »  |  Full Text »  |  PDF »

Berberine suppresses proinflammatory responses through AMPK activation in macrophages.

H. W. Jeong, K. C. Hsu, J.-W. Lee, M. Ham, J. Y. Huh, H. J. Shin, W. S. Kim, and J. B. Kim (2009)
Am J Physiol Endocrinol Metab 296, E955-E964
 |  Abstract »  |  Full Text »  |  PDF »

Rescuing 3T3-L1 Adipocytes from Insulin Resistance Induced by Stimulation of Akt-Mammalian Target of Rapamycin/p70 S6 Kinase (S6K1) Pathway and Serine Phosphorylation of Insulin Receptor Substrate-1: Effect of Reduced Expression of p85{alpha} Subunit of Phosphatidylinositol 3-Kinase and S6K1 Kinase.

R. Adochio, J. W. Leitner, R. Hedlund, and B. Draznin (2009)
Endocrinology 150, 1165-1173
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of Angiotensin Type 2 Receptor Rescues Obesity But Not Hypertension Induced by Overexpression of Angiotensinogen in Adipose Tissue.

L. Yvan-Charvet, F. Massiera, N. Lamande, G. Ailhaud, M. Teboul, N. Moustaid-Moussa, J.-M. Gasc, and A. Quignard-Boulange (2009)
Endocrinology 150, 1421-1428
 |  Abstract »  |  Full Text »  |  PDF »

Heme Oxygenase-1 Induction Remodels Adipose Tissue and Improves Insulin Sensitivity in Obesity-Induced Diabetic Rats.

A. Nicolai, M. Li, D. H. Kim, S. J. Peterson, L. Vanella, V. Positano, A. Gastaldelli, R. Rezzani, L. F. Rodella, G. Drummond, et al. (2009)
Hypertension 53, 508-515
 |  Abstract »  |  Full Text »  |  PDF »

Progress and Challenges in Metabolic Syndrome in Children and Adolescents: A Scientific Statement From the American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular Nursing; and Council on Nutrition, Physical Activity, and Metabolism.

J. Steinberger, S. R. Daniels, R. H. Eckel, L. Hayman, R. H. Lustig, B. McCrindle, and M. L. Mietus-Snyder (2009)
Circulation 119, 628-647
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Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPAR{gamma}-/-, PPAR{delta}-/-, PPAR{gamma}{delta}-/-, or LXR{alpha}{beta}-/- bone marrow.

C. Marathe, M. N. Bradley, C. Hong, L. Chao, D. Wilpitz, J. Salazar, and P. Tontonoz (2009)
J. Lipid Res. 50, 214-224
 |  Abstract »  |  Full Text »  |  PDF »

Inflammation, Insulin Resistance, and Type 2 Diabetes: Back to the Future?.

W. T. Cefalu (2009)
Diabetes 58, 307-308
 |  Full Text »  |  PDF »

Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice.

M. S. Han, K. W. Chung, H. G. Cheon, S. D. Rhee, C.-H. Yoon, M.-K. Lee, K.-W. Kim, and M.-S. Lee (2009)
Diabetes 58, 329-336
 |  Abstract »  |  Full Text »  |  PDF »

Internet-delivered lifestyle physical activity intervention: limited inflammation and antioxidant capacity efficacy in overweight adults.

D. T. Smith, L. J. Carr, C. Dorozynski, and C. Gomashe (2009)
J Appl Physiol 106, 49-56
 |  Abstract »  |  Full Text »  |  PDF »

Changes in the transcriptome of abdominal subcutaneous adipose tissue in response to short-term overfeeding in lean and obese men.

J. Shea, C. R French, J. Bishop, G. Martin, B. Roebothan, D. Pace, D. Fitzpatrick, and G. Sun (2009)
Am. J. Clinical Nutrition 89, 407-415
 |  Abstract »  |  Full Text »  |  PDF »

Inflammation-Associated Serum and Colon Markers as Indicators of Dietary Attenuation of Colon Carcinogenesis in ob/ob Mice.

R. A. Mentor-Marcel, G. Bobe, K. G. Barrett, M. R. Young, P. S. Albert, M. R. Bennink, E. Lanza, and N. H. Colburn (2009)
Cancer Prevention Research 2, 60-69
 |  Abstract »  |  Full Text »  |  PDF »

Chlamydial LPS and high-sensitivity CRP levels in serum are associated with an elevated body mass index in patients with cardiovascular disease.

T. Lajunen, P. Vikatmaa, A. Bloigu, T. Ikonen, M. Lepantalo, P. J. Pussinen, P. Saikku, and M. Leinonen (2008)
Innate Immunity 14, 375-382
 |  Abstract »  |  PDF »

Depression: An Important Comorbidity With Metabolic Syndrome in a General Population.

J. A. Dunbar, P. Reddy, N. Davis-Lameloise, B. Philpot, T. Laatikainen, A. Kilkkinen, S. J. Bunker, J. D. Best, E. Vartiainen, S. Kai Lo, et al. (2008)
Diabetes Care 31, 2368-2373
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db Mice.

Y. Tamura, M. Sugimoto, T. Murayama, Y. Ueda, H. Kanamori, K. Ono, H. Ariyasu, T. Akamizu, T. Kita, M. Yokode, et al. (2008)
Arterioscler Thromb Vasc Biol 28, 2195-2201
 |  Abstract »  |  Full Text »  |  PDF »

Adipose Inflammation, Insulin Resistance, and Cardiovascular Disease.

A. Shah, N. Mehta, and M. P. Reilly (2008)
JPEN J Parenter Enteral Nutr 32, 638-644
 |  Abstract »  |  Full Text »  |  PDF »

Adipose Endocrine Function, Insulin-Like Growth Factor-1 Axis, and Exceptional Survival Beyond 100 Years of Age.

Y. Arai, M. Takayama, Y. Gondo, H. Inagaki, K. Yamamura, S. Nakazawa, T. Kojima, Y. Ebihara, K. Shimizu, Y. Masui, et al. (2008)
J. Gerontol. A Biol. Sci. Med. Sci. 63, 1209-1218
 |  Abstract »  |  Full Text »  |  PDF »

{beta}-Cell Mass and Type 1 Diabetes: Going, Going, Gone?.

E. Akirav, J. A. Kushner, and K. C. Herold (2008)
Diabetes 57, 2883-2888
 |  Abstract »  |  Full Text »  |  PDF »

Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance.

L. Nikonova, R. A. Koza, T. Mendoza, P.-M. Chao, J. P. Curley, and L. P. Kozak (2008)
FASEB J 22, 3925-3937
 |  Abstract »  |  Full Text »  |  PDF »

Visfatin: a new player in mesangial cell physiology and diabetic nephropathy.

H. K. Song, M. H. Lee, B. K. Kim, Y. G. Park, G. J. Ko, Y. S. Kang, J. Y. Han, S. Y. Han, K. H. Han, H. K. Kim, et al. (2008)
Am J Physiol Renal Physiol 295, F1485-F1494
 |  Abstract »  |  Full Text »  |  PDF »

Intricacies of Fat.

L. Stehno-Bittel (2008)
Physical Therapy 88, 1265-1278
 |  Abstract »  |  Full Text »  |  PDF »

Adipocytokines and the Metabolic Complications of Obesity.

N. Rasouli and P. A. Kern (2008)
J. Clin. Endocrinol. Metab. 93, s64-s73
 |  Abstract »  |  Full Text »  |  PDF »

Curative and {beta} cell regenerative effects of {alpha}1-antitrypsin treatment in autoimmune diabetic NOD mice.

M. Koulmanda, M. Bhasin, L. Hoffman, Z. Fan, A. Qipo, H. Shi, S. Bonner-Weir, P. Putheti, N. Degauque, T. A. Libermann, et al. (2008)
PNAS 105, 16242-16247
 |  Abstract »  |  Full Text »  |  PDF »

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6.

B. K. Pedersen and M. A. Febbraio (2008)
Physiol Rev 88, 1379-1406
 |  Abstract »  |  Full Text »  |  PDF »

Adiponectin Blocks Interleukin-18-mediated Endothelial Cell Death via APPL1-dependent AMP-activated Protein Kinase (AMPK) Activation and IKK/NF-{kappa}B/PTEN Suppression.

B. Chandrasekar, W. H. Boylston, K. Venkatachalam, N. J. G. Webster, S. D. Prabhu, and A. J. Valente (2008)
J. Biol. Chem. 283, 24889-24898
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis.

N. Anderson and J. Borlak (2008)
Pharmacol. Rev. 60, 311-357
 |  Abstract »  |  Full Text »  |  PDF »

The Association between Obesity and Asthma: Interactions between Systemic and Airway Inflammation.

T. J. T. Sutherland, J. O. Cowan, S. Young, A. Goulding, A. M. Grant, A. Williamson, K. Brassett, G. P. Herbison, and D. R. Taylor (2008)
Am. J. Respir. Crit. Care Med. 178, 469-475
 |  Abstract »  |  Full Text »  |  PDF »

Adipose Macrophage Infiltration Is Associated With Insulin Resistance and Vascular Endothelial Dysfunction in Obese Subjects.

C. M. Apovian, S. Bigornia, M. Mott, M. R. Meyers, J. Ulloor, M. Gagua, M. McDonnell, D. Hess, L. Joseph, and N. Gokce (2008)
Arterioscler Thromb Vasc Biol 28, 1654-1659
 |  Abstract »  |  Full Text »  |  PDF »

Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice.

R. L. Bradley, J. Y. Jeon, F.-F. Liu, and E. Maratos-Flier (2008)
Am J Physiol Endocrinol Metab 295, E586-E594
 |  Abstract »  |  Full Text »  |  PDF »

ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet.

M. Gupte, C. M. Boustany-Kari, K. Bharadwaj, S. Police, S. Thatcher, M. C. Gong, V. L. English, and L. A. Cassis (2008)
Am J Physiol Regulatory Integrative Comp Physiol 295, R781-R788
 |  Abstract »  |  Full Text »  |  PDF »

CC Chemokine and CC Chemokine Receptor Profiles in Visceral and Subcutaneous Adipose Tissue Are Altered in Human Obesity.

J. Huber, F. W. Kiefer, M. Zeyda, B. Ludvik, G. R. Silberhumer, G. Prager, G. J. Zlabinger, and T. M. Stulnig (2008)
J. Clin. Endocrinol. Metab. 93, 3215-3221
 |  Abstract »  |  Full Text »  |  PDF »

Associations of Adiponectin, Resistin, and Tumor Necrosis Factor-{alpha} with Insulin Resistance.

M.-F. Hivert, L. M. Sullivan, C. S. Fox, D. M. Nathan, R. B. D'Agostino Sr., P. W. F. Wilson, and J. B. Meigs (2008)
J. Clin. Endocrinol. Metab. 93, 3165-3172
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Peroxisome Proliferator-Activated Receptor {beta}/{delta} Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor-{kappa}B Activity via Extracellular Signal-Related Kinase 1/2.

R. Rodriguez-Calvo, L. Serrano, T. Coll, N. Moullan, R. M. Sanchez, M. Merlos, X. Palomer, J. C. Laguna, L. Michalik, W. Wahli, et al. (2008)
Diabetes 57, 2149-2157
 |  Abstract »  |  Full Text »  |  PDF »

Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity.

X. Qi, J. T. Reed, G. Wang, S. Han, E. W. Englander, and G. H. Greeley Jr. (2008)
Am J Physiol Regulatory Integrative Comp Physiol 295, R429-R435
 |  Abstract »  |  Full Text »  |  PDF »

Effect of dermcidin, an antimicrobial peptide, on body fat mobilization in normal mice.

K.-A. Kim, S.-O Ka, W. S. Moon, H.-K. Yi, Y.-H. Lee, K.-B. Kwon, J.-W. Park, and B.-H. Park (2008)
J. Endocrinol. 198, 111-118
 |  Abstract »  |  Full Text »  |  PDF »

Dietary Curcumin Significantly Improves Obesity-Associated Inflammation and Diabetes in Mouse Models of Diabesity.

S. P. Weisberg, R. Leibel, and D. V. Tortoriello (2008)
Endocrinology 149, 3549-3558
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor-{alpha} Antagonism Improves Vasodilation During Hyperinsulinemia in Metabolic Syndrome.

M. Tesauro, F. Schinzari, V. Rovella, D. Melina, N. Mores, A. Barini, M. Mettimano, D. Lauro, M. Iantorno, M. J. Quon, et al. (2008)
Diabetes Care 31, 1439-1441
 |  Abstract »  |  Full Text »  |  PDF »

Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation.

R. A. Johnston, T. A. Theman, F. L. Lu, R. D. Terry, E. S. Williams, and S. A. Shore (2008)
J Appl Physiol 104, 1727-1735
 |  Abstract »  |  Full Text »  |  PDF »

New Role of Resistin in Lipopolysaccharide-Induced Liver Damage in Mice.

J. I. Beier, L. Guo, C. von Montfort, J. P. Kaiser, S. Joshi-Barve, and G. E. Arteel (2008)
J. Pharmacol. Exp. Ther. 325, 801-808
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of Tumor Necrosis Factor (TNF) Receptor Type 1-Mediated TNF-{alpha} Signaling Protected Wistar Rats from Diet-Induced Obesity and Insulin Resistance.

H. Liang, B. Yin, H. Zhang, S. Zhang, Q. Zeng, J. Wang, X. Jiang, L. Yuan, C.-Y. Wang, and Z. Li (2008)
Endocrinology 149, 2943-2951
 |  Abstract »  |  Full Text »  |  PDF »

The Perfect Storm: Obesity, Adipocyte Dysfunction, and Metabolic Consequences.

S. de Ferranti and D. Mozaffarian (2008)
Clin. Chem. 54, 945-955
 |  Abstract »  |  Full Text »  |  PDF »

Energy intake is associated with endotoxemia in apparently healthy men.

J. Amar, R. Burcelin, J. B. Ruidavets, P. D Cani, J. Fauvel, M. C. Alessi, B. Chamontin, and J. Ferrieres (2008)
Am. J. Clinical Nutrition 87, 1219-1223
 |  Abstract »  |  Full Text »  |  PDF »

Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis.

N Beraza, Y Malato, S Vander Borght, C Liedtke, H E Wasmuth, M Dreano, R de Vos, T Roskams, and C Trautwein (2008)
Gut 57, 655-663
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines and {beta}-Cell Biology: from Concept to Clinical Translation.

M. Y. Donath, J. Storling, L. A. Berchtold, N. Billestrup, and T. Mandrup-Poulsen (2008)
Endocr. Rev. 29, 334-350
 |  Abstract »  |  Full Text »  |  PDF »

Visceral Obesity and Plasma Glucose-Insulin Homeostasis: Contributions of Interleukin-6 and Tumor Necrosis Factor-{alpha} in Men.

A. Cartier, I. Lemieux, N. Almeras, A. Tremblay, J. Bergeron, and J.-P. Despres (2008)
J. Clin. Endocrinol. Metab. 93, 1931-1938
 |  Abstract »  |  Full Text »  |  PDF »

Trauma and Hemorrhage-Induced Acute Hepatic Insulin Resistance: Dominant Role of Tumor Necrosis Factor-{alpha}.

J. Xu, H. T. Kim, Y. Ma, L. Zhao, L. Zhai, N. Kokorina, P. Wang, and J. L. Messina (2008)
Endocrinology 149, 2369-2382
 |  Abstract »  |  Full Text »  |  PDF »

Hyperleptinemia without Obesity in Male Mice Lacking Androgen Receptor in Adipose Tissue.

I-C. Yu, H.-Y. Lin, N.-C. Liu, R.-S. Wang, J. D. Sparks, S. Yeh, and C. Chang (2008)
Endocrinology 149, 2361-2368
 |  Abstract »  |  Full Text »  |  PDF »

Tumor necrosis factor-{alpha} directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling.

B. Qin, R. A. Anderson, and K. Adeli (2008)
Am J Physiol Gastrointest Liver Physiol 294, G1120-G1129
 |  Abstract »  |  Full Text »  |  PDF »

Monocyte Chemoattractant Protein-1 Deficiency Fails to Restrain Macrophage Infiltration Into Adipose Tissue.

E. A. Kirk, Z. K. Sagawa, T. O. McDonald, K. D. O'Brien, and J. W. Heinecke (2008)
Diabetes 57, 1254-1261
 |  Abstract »  |  Full Text »  |  PDF »

Apolipoprotein AII Is a Regulator of Very Low Density Lipoprotein Metabolism and Insulin Resistance.

L. W. Castellani, C. N. Nguyen, S. Charugundla, M. M. Weinstein, C. X. Doan, W. S. Blaner, N. Wongsiriroj, and A. J. Lusis (2008)
J. Biol. Chem. 283, 11633-11644
 |  Abstract »  |  Full Text »  |  PDF »

A Prospective Evaluation of Insulin and Insulin-like Growth Factor-I as Risk Factors for Endometrial Cancer.

M. J. Gunter, D. R. Hoover, H. Yu, S. Wassertheil-Smoller, J. E. Manson, J. Li, T. G. Harris, T. E. Rohan, X. Xue, G. Y.F. Ho, et al. (2008)
Cancer Epidemiol. Biomarkers Prev. 17, 921-929
 |  Abstract »  |  Full Text »  |  PDF »

TRB3 suppresses adipocyte differentiation by negatively regulating PPAR{gamma} transcriptional activity.

Y. Takahashi, N. Ohoka, H. Hayashi, and R. Sato (2008)
J. Lipid Res. 49, 880-892
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Attenuates the Action of Insulin in Hepatocytes.

F. Feng, L. Wang, N. Albanese, A. Holmes, and P. Xia (2008)
Endocrinology 149, 1505-1513
 |  Abstract »  |  Full Text »  |  PDF »

Dietary Cholesterol Worsens Adipose Tissue Macrophage Accumulation and Atherosclerosis in Obese LDL Receptor-Deficient Mice.

S. Subramanian, C. Y. Han, T. Chiba, T. S. McMillen, S. A. Wang, A. Haw III, E. A. Kirk, K. D. O'Brien, and A. Chait (2008)
Arterioscler Thromb Vasc Biol 28, 685-691
 |  Abstract »  |  Full Text »  |  PDF »

Association of IL-1ra and Adiponectin With C-Peptide and Remission in Patients With Type 1 Diabetes.

C. Pfleger, H. B. Mortensen, L. Hansen, C. Herder, B. O. Roep, H. Hoey, H.-J. Aanstoot, M. Kocova, N. C. Schloot, and on behalf of the Hvidore Study Group on Childhood (2008)
Diabetes 57, 929-937
 |  Abstract »  |  Full Text »  |  PDF »

Integrating the immune system with the regulation of growth and efficiency.

N. K. Gabler and M. E. Spurlock (2008)
J Anim Sci 86, E64-E74
 |  Abstract »  |  Full Text »  |  PDF »

The importance of treating cardiometabolic risk factors in patients with type 2 diabetes.

A. H Barnett (2008)
Diabetes and Vascular Disease Research 5, 9-14
 |  Abstract »  |  PDF »

Osteopontin Expression in Human and Murine Obesity: Extensive Local Up-Regulation in Adipose Tissue but Minimal Systemic Alterations.

F. W. Kiefer, M. Zeyda, J. Todoric, J. Huber, R. Geyeregger, T. Weichhart, O. Aszmann, B. Ludvik, G. R. Silberhumer, G. Prager, et al. (2008)
Endocrinology 149, 1350-1357
 |  Abstract »  |  Full Text »  |  PDF »

Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species.

Y. Wei, K. Chen, A. T. Whaley-Connell, C. S. Stump, J. A. Ibdah, and J. R. Sowers (2008)
Am J Physiol Regulatory Integrative Comp Physiol 294, R673-R680
 |  Abstract »  |  Full Text »  |  PDF »

HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus.

M. J. Carper, W. T. Cade, M. Cam, S. Zhang, A. Shalev, K. E. Yarasheski, and S. Ramanadham (2008)
Am J Physiol Endocrinol Metab 294, E558-E567
 |  Abstract »  |  Full Text »  |  PDF »

Obesity and Obstructive Sleep Apnea: Pathogenic Mechanisms and Therapeutic Approaches.

A. R. Schwartz, S. P. Patil, A. M. Laffan, V. Polotsky, H. Schneider, and P. L. Smith (2008)
Proceedings of the ATS 5, 185-192
 |  Abstract »  |  Full Text »  |  PDF »

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