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Science 18 August 1972:
Vol. 177. no. 4049, pp. 619 - 621
DOI: 10.1126/science.177.4049.619
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Articles

Nicotine Blocks the Suckling-Induced Rise in Circulating Prolactin in Lactating Rats

Charles A. Blake 1 and Charles H. Sawyer 1

1 Department of Anatomy and Brain Research Institute, School of Medicine, University of California, Los Angeles 90024

In lactating rats the rapid suckling-induced release of pituitary prolactin into circulating blood is inhibited by a subcutaneous injection of nicotine. This treatment does not block the lesser "stress-induced" rise in prolactin in response to either. Although nicotine may impair milk production by its effect on prolactin release, it does not appear to block milk ejection from the lactating mammary gland.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Influence of Maternal Nicotine Exposure on Neonatal Rat Bone: Protective Effect of Pentoxifylline.
S. Kurtoglu, T. Gunes, E. Koklu, O. Bastug, O. Canoz, M. Kula, F. Bastug, and I. Gunes (2007)
Experimental Biology and Medicine 232, 398-405
   Abstract »    Full Text »    PDF »
Prolactin: Structure, Function, and Regulation of Secretion.
M. E. Freeman, B. Kanyicska, A. Lerant, and G. Nagy (2000)
Physiol Rev 80, 1523-1631
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)