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Science 4 September 1942:
Vol. 96. no. 2488, pp. 236 - 237
DOI: 10.1126/science.96.2488.236
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Articles

MECHANISM OF SULFONAMIDE ACTION. II. INHIBITION OF BACTERIAL RESPIRATION BY SULFANILAMIDE AND BY ITS INACTIVE ISOMERS

ORVILLE WYSS 1, FREDE B. STRANDSKOV 1, and FRANZ C. SCHMELKES 1

1 WALLACE AND TIERNAN PRODUCTS, INC., BELLEVILLE, N. J.

These data indicate that the inhibition of bacterial respiration is not a suitable criterion for the presence or absence of true sulfonamide activity.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)