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Science 1 August 2008:
Vol. 321. no. 5889, p. 640
DOI: 10.1126/science.1153484
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Technical Comments

Comment on "Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain"

Seth D. Friedman

Manganas et al. (Reports, 9 November 2007, p. 980) used a metabolic biomarker identified in vitro to characterize the existence of neural progenitor cells in vivo. Although their detailed experiments and general approach are laudable, aspects of their magnetic resonance spectroscopy data and analyses raise questions about their results.

Department of Radiology, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA. E-mail: sethf{at}u.washington.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)