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Science 1 December 2006:
Vol. 314. no. 5804, pp. 1410 - 1411
DOI: 10.1126/science.1134040

Perspective

Brassinosteroid Signaling: A Paradigm for Steroid Hormone Signaling from the Cell Surface

Youssef Belkhadir and Joanne Chory*

Plants use the coordinated action of several small-molecule hormones to grow and develop optimally in response to a changing environment. Among these hormones are the brassinosteroids (BRs), the polyhydroxylated steroid hormones of plants. BRs bind a small family of leucine-rich repeat receptor kinases at the cell surface, thereby initiating an intracellular signal transduction cascade that results in the altered expression of hundreds of genes.

Plant Biology Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

* To whom correspondence should be addressed. E-mail: chory{at}salk.edu

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