Related Content
Search Google Scholar for:
More Information
Related Jobs from ScienceCareers
|
|
Science 8 September 2006: Vol. 313. no. 5792, pp. 1448 - 1450 DOI: 10.1126/science.1128721
|
|
Reports
Gene Transposition as a Cause of Hybrid Sterility in Drosophila
John P. Masly,1*
Corbin D. Jones,2
Mohamed A. F. Noor,3
John Locke,4
H. Allen Orr1
We describe reproductive isolation caused by a gene transposition. In certain Drosophila melanogaster D. simulans hybrids, hybrid male sterility is caused by the lack of a single-copy gene essential for male fertility, JYAlpha. This gene is located on the fourth chromosome of D. melanogaster but on the third chromosome of D. simulans. Genomic and molecular analyses show that JYAlpha transposed to the third chromosome during the evolutionary history of the D. simulans lineage. Because of this transposition, a fraction of hybrids completely lack JYAlpha and are sterile, representing reproductive isolation without sequence evolution.
1 Department of Biology, University of Rochester, Rochester, NY 14627, USA.
2 Department of Biology and Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC 27599, USA.
3 Developmental, Cell, and Molecular Biology Group/Department of Biology, Duke University, Durham, NC 27708, USA.
4 Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
* To whom correspondence should be addressed. E-mail: msly{at}mail.rochester.edu
Read the Full Text
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Genetics and Lineage-Specific Evolution of a Lethal Hybrid Incompatibility Between Drosophila mauritiana and Its Sibling Species.
- M. V. Cattani and D. C. Presgraves (2009)
Genetics
181, 1545-1555
| Abstract »
| Full Text »
| PDF »
- Evolution of the Drosophila Nuclear Pore Complex Results in Multiple Hybrid Incompatibilities.
- S. Tang and D. C. Presgraves (2009)
Science
323, 779-782
| Abstract »
| Full Text »
| PDF »
- Divergent Evolution of Duplicate Genes Leads to Genetic Incompatibilities Within A. thaliana.
- D. Bikard, D. Patel, C. Le Mette, V. Giorgi, C. Camilleri, M. J. Bennett, and O. Loudet (2009)
Science
323, 623-626
| Abstract »
| Full Text »
| PDF »
- A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase.
- O. Mihola, Z. Trachtulec, C. Vlcek, J. C. Schimenti, and J. Forejt (2009)
Science
323, 373-375
| Abstract »
| Full Text »
| PDF »
- A Single Gene Causes Both Male Sterility and Segregation Distortion in Drosophila Hybrids.
- N. Phadnis and H. A. Orr (2009)
Science
323, 376-379
| Abstract »
| Full Text »
| PDF »
- The strength and genetic basis of reproductive isolating barriers in flowering plants.
- D. B Lowry, J. L Modliszewski, K. M Wright, C. A Wu, and J. H Willis (2008)
Phil Trans R Soc B
363, 3009-3021
| Abstract »
| Full Text »
| PDF »
- From the Cover: A triallelic system of S5 is a major regulator of the reproductive barrier and compatibility of indica-japonica hybrids in rice.
- J. Chen, J. Ding, Y. Ouyang, H. Du, J. Yang, K. Cheng, J. Zhao, S. Qiu, X. Zhang, J. Yao, et al. (2008)
PNAS
105, 11436-11441
| Abstract »
| Full Text »
| PDF »
- Pedigrees, assortative mating and speciation in Darwin's finches.
- P. R Grant and B. R. Grant (2008)
Proc R Soc B
275, 661-668
| Abstract »
| Full Text »
| PDF »
- Significant Variation for Fitness Impacts of ETS Loci in Hybrids between Populations of Tigriopus californicus.
- C. S. Willett (2008)
J. Hered.
99, 56-65
| Abstract »
| Full Text »
| PDF »
- A Genomewide Study of Reproductive Barriers Between Allopatric Populations of a Homosporous Fern, Ceratopteris richardii.
- T. Nakazato, M.-K. Jung, E. A. Housworth, L. H. Rieseberg, and G. J. Gastony (2007)
Genetics
177, 1141-1150
| Abstract »
| Full Text »
| PDF »
- Speciation in Drosophila: From Phenotypes to Molecules.
- H. A. Orr, J. Masly, and N. Phadnis (2007)
J. Hered.
98, 103-110
| Abstract »
| Full Text »
| PDF »
- Pervasive Adaptive Evolution among Interactors of the Drosophila Hybrid Inviability Gene, Nup96.
- D. C. Presgraves and W. Stephan (2007)
Mol. Biol. Evol.
24, 306-314
| Abstract »
| Full Text »
| PDF »
|
|