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Science 8 September 2006:
Vol. 313. no. 5792, p. 1389
DOI: 10.1126/science.1128655
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Technical Comments

Comment on "Transitions to Asexuality Result in Excess Amino Acid Substitutions"

Roger Butlin

Paland and Lynch (Reports, 17 February 2006, p. 990) showed that in Daphnia pulex, the ratio of amino acid replacement to silent substitution in mitochondrial genes is higher in asexual lineages than in sexual lineages. If this base-composition bias is maintained by selection, it too should alter following transitions in reproductive mode. Analysis reveals no such change in the genomes of D. pulex.

Department of Animal and Plant Sciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.

E-mail: r.k.butlin{at}sheffield.ac.uk

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Science. ISSN 0036-8075 (print), 1095-9203 (online)