Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Science Policy Alerts

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Originally published in Science Express on 20 July 2006
Science 25 August 2006:
Vol. 313. no. 5790, pp. 1118 - 1122
DOI: 10.1126/science.1127593
Prev | Table of Contents | Next

Reports

Brassinosteroids Regulate Dissociation of BKI1, a Negative Regulator of BRI1 Signaling, from the Plasma Membrane

Xuelu Wang and Joanne Chory*

Brassinosteroids, the steroid hormones of plants, are perceived at the plasma membrane by a leucine-rich repeat receptor serine/threonine kinase called BRI1. We report a BRI1-interacting protein, BKI1, which is a negative regulator of brassinosteroid signaling. Brassinosteroids cause the rapid dissociation of BKI1–yellow fluorescent protein from the plasma membrane in a process that is dependent on BRI1-kinase. BKI1 is a substrate of BRI1 kinase and limits the interaction of BRI1 with its proposed coreceptor, BAK1, suggesting that BKI1 prevents the activation of BRI1.

Howard Hughes Medical Institute and Plant Biology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

* To whom correspondence should be addressed. E-mail: chory{at}salk.edu

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
BSKs Mediate Signal Transduction from the Receptor Kinase BRI1 in Arabidopsis.
W. Tang, T.-W. Kim, J. A. Oses-Prieto, Y. Sun, Z. Deng, S. Zhu, R. Wang, A. L. Burlingame, and Z.-Y. Wang (2008)
Science 321, 557-560
   Abstract »    Full Text »    PDF »
From the Cover: Modulation of brassinosteroid-regulated gene expression by jumonji domain-containing proteins ELF6 and REF6 in Arabidopsis.
X. Yu, L. Li, L. Li, M. Guo, J. Chory, and Y. Yin (2008)
PNAS 105, 7618-7623
   Abstract »    Full Text »    PDF »
Signalling through kinase-defective domains: the prevalence of atypical receptor-like kinases in plants.
E. Castells and J. M. Casacuberta (2007)
J. Exp. Bot.
   Abstract »    Full Text »    PDF »
Endosomal signaling of plant steroid receptor kinase BRI1.
N. Geldner, D. L. Hyman, X. Wang, K. Schumacher, and J. Chory (2007)
Genes & Dev. 21, 1598-1602
   Abstract »    Full Text »    PDF »
Flowering Newsletter bibliography for 2006.
(2007)
J. Exp. Bot.
   Full Text »    PDF »
A Comprehensive Analysis of the 14-3-3 Interactome in Barley Leaves Using a Complementary Proteomics and Two-Hybrid Approach.
P. J. Schoonheim, H. Veiga, D. da Costa Pereira, G. Friso, K. J. van Wijk, and A. H. de Boer (2007)
Plant Physiology 143, 670-683
   Abstract »    Full Text »    PDF »
Brassinosteroid Signaling Pathway.
Y. Belkhadir, X. Wang, and J. Chory (2006)
Sci. STKE 2006, cm4
   Abstract »    Full Text »    PDF »
Arabidopsis Brassinosteroid Signaling Pathway.
Y. Belkhadir, X. Wang, and J. Chory (2006)
Sci. STKE 2006, cm5
   Abstract »    Full Text »    PDF »
Brassinosteroid Signaling: A Paradigm for Steroid Hormone Signaling from the Cell Surface.
Y. Belkhadir and J. Chory (2006)
Science 314, 1410-1411
   Abstract »    Full Text »    PDF »
Advances in Understanding Brassinosteroid Signaling.
R. Karlova and S. C. de Vries (2006)
Sci. STKE 2006, pe36
   Abstract »    Full Text »    PDF »


ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)