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Science 20 January 2006:
Vol. 311. no. 5759, pp. 353 - 355
DOI: 10.1126/science.1119790

Reports

Phospholipid Nonwoven Electrospun Membranes

Matthew G. McKee, John M. Layman, Matthew P. Cashion, Timothy E. Long*

Nonwoven fibrous membranes were formed from electrospinning lecithin solutions in a single processing step. As the concentration of lecithin increased, the micellar morphology evolved from spherical to cylindrical, and at higher concentrations the cylindrical micelles overlapped and entangled in a fashion similar to polymers in semi-dilute or concentrated solutions. At concentrations above the onset of entanglements of the wormlike micelles, electrospun fibers were fabricated with diameters on the order of 1 to 5 micrometers. The electrospun phospholipid fibers offer the potential for direct fabrication of biologically based, high-surface-area membranes without the use of multiple synthetic steps, complicated electrospinning designs, or postprocessing surface treatments.

Department of Chemistry, Macromolecules and Interfaces Institute (MII), Virginia Tech, Blacksburg, VA 24061, USA.

* To whom correspondence should be addressed. E-mail: telong{at}vt.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)