Reports

Induction of Protein Secretory Pathway Is Required for Systemic Acquired Resistance

Dong Wang, Natalie D. Weaver, Meenu Kesarwani,^* Xinnian Dong

In plants, systemic acquired resistance (SAR) is established as a result of NPR1-regulated expression of pathogenesis-related (PR) genes. Using gene expression profiling in Arabidopsis, we found that in addition to controlling the expression of PR genes, NPR1 also directly controls the expression of the protein secretory pathway genes. Up-regulation of these genes is essential for SAR, because mutations in some of them diminished the secretion of PR proteins (for example, PR1), resulting in reduced resistance. We provide evidence that NPR1 coordinately regulates these secretion-related genes through a previously undescribed cis-element. Activation of this cis-element is controlled by a transcription factor that is translocated into the nucleus upon SAR induction.

Developmental, Cell and Molecular Biology Group, Department of Biology, Post Office Box 91000, Duke University, Durham, NC 27708, USA.

^* Present address: Massachusetts General Hospital, Department of Surgery, Boston, MA 02114, USA.

To whom correspondence should be addressed. E-mail: xdong{at}duke.edu

Read the Full Text

Activation of Defense Response Pathways by OGs and Flg22 Elicitors in Arabidopsis Seedlings.

C. Denoux, R. Galletti, N. Mammarella, S. Gopalan, D. Werck, G. De Lorenzo, S. Ferrari, F. M. Ausubel, and J. Dewdney (2008)
Mol Plant
 |  Abstract »  |  Full Text »  |  PDF »

Genome-Wide Expression Profiling Arabidopsis at the Stage of Golovinomyces cichoracearum Haustorium Formation.

G. Fabro, J. A. Di Rienzo, C. A. Voigt, T. Savchenko, K. Dehesh, S. Somerville, and M. E. Alvarez (2008)
Plant Physiology 146, 1421-1439
 |  Abstract »  |  Full Text »  |  PDF »

BAX Inhibitor-1 Modulates Endoplasmic Reticulum Stress-mediated Programmed Cell Death in Arabidopsis.

N. Watanabe and E. Lam (2008)
J. Biol. Chem. 283, 3200-3210
 |  Abstract »  |  Full Text »  |  PDF »

Salicylic Acid and Systemic Acquired Resistance Play a Role in Attenuating Crown Gall Disease Caused by Agrobacterium tumefaciens.

A. Anand, S. R. Uppalapati, C.-M. Ryu, S. N. Allen, L. Kang, Y. Tang, and K. S. Mysore (2008)
Plant Physiology 146, 703-715
 |  Abstract »  |  Full Text »  |  PDF »

A Proteomics Study of Brassinosteroid Response in Arabidopsis.

Z. Deng, X. Zhang, W. Tang, J. A. Oses-Prieto, N. Suzuki, J. M. Gendron, H. Chen, S. Guan, R. J. Chalkley, T. K. Peterman, et al. (2007)
Mol. Cell. Proteomics 6, 2058-2071
 |  Abstract »  |  Full Text »  |  PDF »

The syntaxin SYP132 contributes to plant resistance against bacteria and secretion of pathogenesis-related protein 1.

M. Kalde, T. S. Nuhse, K. Findlay, and S. C. Peck (2007)
PNAS 104, 11850-11855
 |  Abstract »  |  Full Text »  |  PDF »

MYC2 Differentially Modulates Diverse Jasmonate-Dependent Functions in Arabidopsis.

B. Dombrecht, G. P. Xue, S. J. Sprague, J. A. Kirkegaard, J. J. Ross, J. B. Reid, G. P. Fitt, N. Sewelam, P. M. Schenk, J. M. Manners, et al. (2007)
PLANT CELL 19, 2225-2245
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Interactions of TGA Transcription Factors in the Regulation of Pathogenesis-Related Genes and Disease Resistance in Arabidopsis.

M. Kesarwani, J. Yoo, and X. Dong (2007)
Plant Physiology 144, 336-346
 |  Abstract »  |  Full Text »  |  PDF »

Heterotrimeric G protein signaling in the Arabidopsis unfolded protein response.

S. Wang, S. Narendra, and N. Fedoroff (2007)
PNAS 104, 3817-3822
 |  Abstract »  |  Full Text »  |  PDF »

Targeted alterations in iron homeostasis underlie plant defense responses.

G. Liu, D. L. Greenshields, R. Sammynaiken, R. N. Hirji, G. Selvaraj, and Y. Wei (2007)
J. Cell Sci. 120, 596-605
 |  Abstract »  |  Full Text »  |  PDF »

Functional Profiling Reveals That Only a Small Number of Phytochrome-Regulated Early-Response Genes in Arabidopsis Are Necessary for Optimal Deetiolation.

R. Khanna, Y. Shen, G. Toledo-Ortiz, E. A. Kikis, H. Johannesson, Y.-S. Hwang, and P. H. Quail (2006)
PLANT CELL 18, 2157-2171
 |  Abstract »  |  Full Text »  |  PDF »

The Arabidopsis Flavin-Dependent Monooxygenase FMO1 Is an Essential Component of Biologically Induced Systemic Acquired Resistance.

T. E. Mishina and J. Zeier (2006)
Plant Physiology 141, 1666-1675
 |  Abstract »  |  Full Text »  |  PDF »

A bacterial virulence protein suppresses host innate immunity to cause plant disease..

K. Nomura, S. DebRoy, Y. H. Lee, N. Pumplin, J. Jones, and S. Y. He (2006)
Science 313, 220-223
 |  Abstract »  |  Full Text »  |  PDF »

POXO: a web-enabled tool series to discover transcription factor binding sites..

M. Kankainen, P. Pehkonen, P. Rosenstom, P. Toronen, G. Wong, and L. Holm (2006)
Nucleic Acids Res. 34, W534-W540
 |  Abstract »  |  Full Text »  |  PDF »

Fitness Benefits of Systemic Acquired Resistance During Hyaloperonospora parasitica Infection in Arabidopsis thaliana.

A. J. Heidel and X. Dong (2006)
Genetics 173, 1621-1628
 |  Abstract »  |  Full Text »  |  PDF »

Proteomic analysis of differentially expressed proteins in fungal elicitor-treated Arabidopsis cell cultures.

S. Chivasa, J. M Hamilton, R. S Pringle, B. K Ndimba, W. J Simon, K. Lindsey, and A. R Slabas (2006)
J. Exp. Bot. 57, 1553-1562
 |  Abstract »  |  Full Text »  |  PDF »

Golgi-Mediated Vacuolar Sorting of the Endoplasmic Reticulum Chaperone BiP May Play an Active Role in Quality Control within the Secretory Pathway.

P. Pimpl, J. P. Taylor, C. Snowden, S. Hillmer, D. G. Robinson, and J. Denecke (2006)
PLANT CELL 18, 198-211
 |  Abstract »  |  Full Text »  |  PDF »

ADVERTISEMENT

ADVERTISEMENT

To Advertise   |   Find Products