Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Originally published in Science Express on 12 September 2002
Science 18 October 2002:
Vol. 298. no. 5593, pp. 601 - 604
DOI: 10.1126/science.1073823
Prev | Table of Contents | Next

Reports

A Stem Cell Molecular Signature

Natalia B. Ivanova, John T. Dimos, Christoph Schaniel, Jason A. Hackney, Kateri A. Moore, Ihor R. Lemischka*

Mechanisms regulating self-renewal and cell fate decisions in mammalian stem cells are poorly understood. We determined global gene expression profiles for mouse and human hematopoietic stem cells and other stages of the hematopoietic hierarchy. Murine and human hematopoietic stem cells share a number of expressed gene products, which define key conserved regulatory pathways in this developmental system. Moreover, in the mouse, a portion of the genetic program of hematopoietic stem cells is shared with embryonic and neural stem cells. This overlapping set of gene products represents a molecular signature of stem cells.

Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
*   To whom correspondence should be addressed: E-mail: ilemischka{at}molbio.princeton.edu

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Diverse Adult Stem Cells Share Specific Higher-Order Patterns of Gene Expression.
J. M. Doherty, M. J. Geske, T. S. Stappenbeck, and J. C. Mills (2008)
Stem Cells 26, 2124-2130
   Abstract »    Full Text »    PDF »
c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo.
C. He, H. Hu, R. Braren, S.-Y. Fong, A. Trumpp, T. R. Carlson, and R. A. Wang (2008)
Development 135, 2467-2477
   Abstract »    Full Text »    PDF »
Cancer Stem Cells and the Ontogeny of Lung Cancer.
C. D. Peacock and D. N. Watkins (2008)
J. Clin. Oncol. 26, 2883-2889
   Abstract »    Full Text »    PDF »
CXCR4+/FLK-1+ Biomarkers Select a Cardiopoietic Lineage from Embryonic Stem Cells.
T. J. Nelson, R. S. Faustino, A. Chiriac, R. Crespo-Diaz, A. Behfar, and A. Terzic (2008)
Stem Cells 26, 1464-1473
   Abstract »    Full Text »    PDF »
Hypoxia-Inducible Factor-2{alpha} Transactivates Abcg2 and Promotes Cytoprotection in Cardiac Side Population Cells.
C. M. Martin, A. Ferdous, T. Gallardo, C. Humphries, H. Sadek, A. Caprioli, J. A. Garcia, L. I. Szweda, M. G. Garry, and D. J. Garry (2008)
Circ. Res. 102, 1075-1081
   Abstract »    Full Text »    PDF »
The role of the chromatin remodeler Mi-2{beta} in hematopoietic stem cell self-renewal and multilineage differentiation.
T. Yoshida, I. Hazan, J. Zhang, S. Y. Ng, T. Naito, H. J. Snippert, E. J. Heller, X. Qi, L. N. Lawton, C. J. Williams, et al. (2008)
Genes & Dev. 22, 1174-1189
   Abstract »    Full Text »    PDF »
Functional Network Reconstruction Reveals Somatic Stemness Genetic Maps and Dedifferentiation-Like Transcriptome Reprogramming Induced by GATA2.
T.-S. Huang, J.-Y. Hsieh, Y.-H. Wu, C.-H. Jen, Y.-H. Tsuang, S.-H. Chiou, J. Partanen, H. Anderson, T. Jaatinen, Y.-H. Yu, et al. (2008)
Stem Cells 26, 1186-1201
   Abstract »    Full Text »    PDF »
Molecular basis of pluripotency.
L. Chen and G. Q. Daley (2008)
Hum. Mol. Genet. 17, R23-R27
   Abstract »    Full Text »    PDF »
Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo.
J. K. Alder, R. W. Georgantas III, R. L. Hildreth, I. M. Kaplan, S. Morisot, X. Yu, M. McDevitt, and C. I. Civin (2008)
J. Immunol. 180, 5645-5652
   Abstract »    Full Text »    PDF »
Targeting Ras in Myeloid Leukemias.
B. S. Braun and K. Shannon (2008)
Clin. Cancer Res. 14, 2249-2252
   Abstract »    Full Text »    PDF »
Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Proteome Quantitation of Mouse Embryonic Stem Cells to a Depth of 5,111 Proteins.
J. Graumann, N. C. Hubner, J. B. Kim, K. Ko, M. Moser, C. Kumar, J. Cox, H. Scholer, and M. Mann (2008)
Mol. Cell. Proteomics 7, 672-683
   Abstract »    Full Text »    PDF »
Genes Involved in Post-Transcriptional Regulation Are Overrepresented in Stem/Progenitor Spermatogonia of Cryptorchid Mouse Testes.
K. E. Orwig, B.-Y. Ryu, S. R. Master, B. T. Phillips, M. Mack, M. R. Avarbock, L. Chodosh, and R. L. Brinster (2008)
Stem Cells 26, 927-938
   Abstract »    Full Text »    PDF »
Junctional adhesion molecule-A, JAM-A, is a novel cell-surface marker for long-term repopulating hematopoietic stem cells.
Y. Sugano, M. Takeuchi, A. Hirata, H. Matsushita, T. Kitamura, M. Tanaka, and A. Miyajima (2008)
Blood 111, 1167-1172
   Abstract »    Full Text »    PDF »
Human Multipotent Stromal Cells Undergo Sharp Transition from Division to Development in Culture.
B. L. Larson, J. Ylostalo, and D. J. Prockop (2008)
Stem Cells 26, 193-201
   Abstract »    Full Text »    PDF »
Transcriptional Analysis of Quiescent and Proliferating CD34+ Human Hemopoietic Cells from Normal and Chronic Myeloid Leukemia Sources.
S. M. Graham, J. K. Vass, T. L. Holyoake, and G. J. Graham (2007)
Stem Cells 25, 3111-3120
   Abstract »    Full Text »    PDF »
Evolution of the bilaterian germ line: lineage origin and modulation of specification mechanisms.
C. G. M. Extavour (2007)
Integr. Comp. Biol. 47, 770-785
   Abstract »    Full Text »    PDF »
Paving the road for lung stem cell biology: bronchioalveolar stem cells and other putative distal lung stem cells.
C. F. Kim (2007)
Am J Physiol Lung Cell Mol Physiol 293, L1092-L1098
   Abstract »    Full Text »    PDF »
Pedigreed Primate Embryonic Stem Cells Express Homogeneous Familial Gene Profiles.
C. S. Navara, J. D. Mich-Basso, C. J. Redinger, A. Ben-Yehudah, E. Jacoby, E. Kovkarova-Naumovski, M. Sukhwani, K. Orwig, N. Kaminski, C. A. Castro, et al. (2007)
Stem Cells 25, 2695-2704
   Abstract »    Full Text »    PDF »
Endoglin Is Not Critical for Hematopoietic Stem Cell Engraftment and Reconstitution but Regulates Adult Erythroid Development.
J. L. Moody, S. Singbrant, G. Karlsson, U. Blank, M. Aspling, J. Flygare, D. Bryder, and S. Karlsson (2007)
Stem Cells 25, 2809-2819
   Abstract »    Full Text »    PDF »
Unique Glycerophospholipid Signature in Retinal Stem Cells Correlates with Enzymatic Functions of Diverse Long-Chain Acyl-CoA Synthetases.
J. Li, Z. Cui, S. Zhao, and R. L. Sidman (2007)
Stem Cells 25, 2864-2873
   Abstract »    Full Text »    PDF »
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells.
Y.-H. Loh, W. Zhang, X. Chen, J. George, and H.-H. Ng (2007)
Genes & Dev. 21, 2545-2557
   Abstract »    Full Text »    PDF »
Inhibition of Histone Deacetylase Activates Side Population Cells in Kidney and Partially Reverses Chronic Renal Injury.
N. Imai, K. Hishikawa, T. Marumo, J. Hirahashi, T. Inowa, Y. Matsuzaki, H. Okano, T. Kitamura, D. Salant, and T. Fujita (2007)
Stem Cells 25, 2469-2475
   Abstract »    Full Text »    PDF »
Concise Review: Trends in Stem Cell Proteomics.
H. Baharvand, A. Fathi, D. van Hoof, and G. H. Salekdeh (2007)
Stem Cells 25, 1888-1903
   Abstract »    Full Text »    PDF »
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis.
J. L. Attema, P. Papathanasiou, E. C. Forsberg, J. Xu, S. T. Smale, and I. L. Weissman (2007)
PNAS 104, 12371-12376
   Abstract »    Full Text »    PDF »
Inference, Validation, and Dynamic Modeling of Transcription Networks in Multipotent Hematopoietic Cells.
S. SONEJI, S. HUANG, M. LOOSE, I. J. DONALDSON, R. PATIENT, B. GOTTGENS, T. ENVER, and G. MAY (2007)
Ann. N.Y. Acad. Sci. 1106, 30-40
   Abstract »    Full Text »    PDF »
Short-term pretreatment with low-dose hydrogen peroxide enhances the efficacy of bone marrow cells for therapeutic angiogenesis.
M. Kubo, T.-S. Li, R. Suzuki, M. Ohshima, S.-L. Qin, and K. Hamano (2007)
Am J Physiol Heart Circ Physiol 292, H2582-H2588
   Abstract »    Full Text »    PDF »
Transcription Profiling of Adult and Fetal Human Neuroprogenitors Identifies Divergent Paths to Maintain the Neuroprogenitor Cell State.
M. Maisel, A. Herr, J. Milosevic, A. Hermann, H.-J. Habisch, S. Schwarz, M. Kirsch, G. Antoniadis, R. Brenner, S. Hallmeyer-Elgner, et al. (2007)
Stem Cells 25, 1231-1240
   Abstract »    Full Text »    PDF »
HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.
M. Magnusson, A. C. M. Brun, N. Miyake, J. Larsson, M. Ehinger, J. M. Bjornsson, A. Wutz, M. Sigvardsson, and S. Karlsson (2007)
Blood 109, 3687-3696
   Abstract »    Full Text »    PDF »
NOV (CCN3) Functions as a Regulator of Human Hematopoietic Stem or Progenitor Cells.
R. Gupta, D. Hong, F. Iborra, S. Sarno, and T. Enver (2007)
Science 316, 590-593
   Abstract »    Full Text »    PDF »
Molecular profile of mouse stromal mesenchymal stem cells.
S. Chateauvieux, J.-L. Ichante, B. Delorme, V. Frouin, G. Pietu, A. Langonne, N. Gallay, L. Sensebe, M. T. Martin, K. A. Moore, et al. (2007)
Physiol Genomics 29, 128-138
   Abstract »    Full Text »    PDF »
Genome-Wide Differential Gene Expression Profiling of Human Bone Marrow Stromal Cells.
J. A. Jeong, K.-M. Ko, S. Bae, C.-J. Jeon, G. Young Koh, and H. Kim (2007)
Stem Cells 25, 994-1002
   Abstract »    Full Text »    PDF »
Report on the Workshop "New Technologies in Stem Cell Research," Society for Pediatric Research, San Francisco, California, April 29, 2006.
J. C. Cheng, K. M. Sakamoto, E. M. Horwitz, S. L. Karsten, L. Shoemaker, H. I. Kornblumc, and P. Malik (2007)
Stem Cells 25, 1070-1088
   Abstract »    Full Text »    PDF »
Crucial Role of Bysl in Mammalian Preimplantation Development as an Integral Factor for 40S Ribosome Biogenesis.
K. Adachi, C. Soeta-Saneyoshi, H. Sagara, and Y. Iwakura (2007)
Mol. Cell. Biol. 27, 2202-2214
   Abstract »    Full Text »    PDF »
Differences between human embryonic stem cell lines.
C. Allegrucci and L.E. Young (2007)
Hum. Reprod. Update 13, 103-120
   Abstract »    Full Text »    PDF »
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
O. S. Kustikova, H. Geiger, Z. Li, M. H. Brugman, S. M. Chambers, C. A. Shaw, K. Pike-Overzet, D. d. Ridder, F. J. T. Staal, G. v. Keudell, et al. (2007)
Blood 109, 1897-1907
   Abstract »    Full Text »    PDF »
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.
M. Vooijs, C.-T. Ong, B. Hadland, S. Huppert, Z. Liu, J. Korving, M. van den Born, T. Stappenbeck, Y. Wu, H. Clevers, et al. (2007)
Development 134, 535-544
   Abstract »    Full Text »    PDF »
HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemia.
G. Strathdee, A. Sim, R. Soutar, T. L. Holyoake, and R. Brown (2007)
Carcinogenesis 28, 299-309
   Abstract »    Full Text »    PDF »
GATA2 functions at multiple steps in hemangioblast development and differentiation.
J. J. Lugus, Y. S. Chung, J. C. Mills, S.-I. Kim, J. A. Grass, M. Kyba, J. M. Doherty, E. H. Bresnick, and K. Choi (2007)
Development 134, 393-405
   Abstract »    Full Text »    PDF »
Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.
K. Ogawa, A. Saito, H. Matsui, H. Suzuki, S. Ohtsuka, D. Shimosato, Y. Morishita, T. Watabe, H. Niwa, and K. Miyazono (2007)
J. Cell Sci. 120, 55-65
   Abstract »    Full Text »    PDF »
Identification, characterization and co-localization of label-retaining cell population in mouse endometrium with typical undifferentiated markers.
I. Cervello, J.A. Martinez-Conejero, J.A. Horcajadas, A. Pellicer, and C. Simon (2007)
Hum. Reprod. 22, 45-51
   Abstract »    Full Text »    PDF »
Reprogramming somatic cells into stem cells..
R. Alberio, K. H Campbell, and A. D Johnson (2006)
Reproduction 132, 709-720
   Abstract »    Full Text »    PDF »
Repression of Nanog Gene Transcription by Tcf3 Limits Embryonic Stem Cell Self-Renewal.
L. Pereira, F. Yi, and B. J. Merrill (2006)
Mol. Cell. Biol. 26, 7479-7491
   Abstract »    Full Text »    PDF »
Genomics and Proteomics of Bone Cancer..
A. G. Marguiles, V. S. Klimberg, S. Bhattacharrya, D. Gaddy, and L. J. Suva (2006)
Clin. Cancer Res. 12, 6217s-6221s
   Abstract »    Full Text »    PDF »
Gene Expression Profiling of Mouse Embryonic Stem Cell Subpopulations.
T. Furusawa, M. Ikeda, F. Inoue, K. Ohkoshi, T. Hamano, and T. Tokunaga (2006)
Biol Reprod 75, 555-561
   Abstract »    Full Text »    PDF »
Putative "Stemness" Gene Jam-B Is Not Required for Maintenance of Stem Cell State in Embryonic, Neural, or Hematopoietic Stem Cells..
T. Sakaguchi, M. Nishimoto, S. Miyagi, A. Iwama, Y. Morita, N. Iwamori, H. Nakauchi, H. Kiyonari, M. Muramatsu, and A. Okuda (2006)
Mol. Cell. Biol. 26, 6557-6570
   Abstract »    Full Text »    PDF »
Isolation and Characterization of Multipotent Progenitor Cells from the Bowman's Capsule of Adult Human Kidneys.
C. Sagrinati, G. S. Netti, B. Mazzinghi, E. Lazzeri, F. Liotta, F. Frosali, E. Ronconi, C. Meini, M. Gacci, R. Squecco, et al. (2006)
J. Am. Soc. Nephrol. 17, 2443-2456
   Abstract »    Full Text »    PDF »
Integrins Are Markers of Human Neural Stem Cells.
P. E. Hall, J. D. Lathia, N. G. A. Miller, M. A. Caldwell, and C. Ffrench-Constant (2006)
Stem Cells 24, 2078-2084
   Abstract »    Full Text »    PDF »
Increased "Vigilance" of Antioxidant Mechanisms in Neural Stem Cells Potentiates Their Capability to Resist Oxidative Stress.
L. Madhavan, V. Ourednik, and J. Ourednik (2006)
Stem Cells 24, 2110-2119
   Abstract »    Full Text »    PDF »
Lefty at the Crossroads of "Stemness" and Differentiative Events.
S. Tabibzadeh and A. Hemmati-Brivanlou (2006)
Stem Cells 24, 1998-2006
   Abstract »    Full Text »    PDF »
Defective Ribosomal Protein Gene Expression Alters Transcription, Translation, Apoptosis, and Oncogenic Pathways in Diamond-Blackfan Anemia.
H. T. Gazda, A. T. Kho, D. Sanoudou, J. M. Zaucha, I. S. Kohane, C. A. Sieff, and A. H. Beggs (2006)
Stem Cells 24, 2034-2044
   Abstract »    Full Text »    PDF »
Identification of regulatory modules by co-clustering latent variable models: stem cell differentiation.
J.-G. Joung, D. Shin, R. H. Seong, and B.-T. Zhang (2006)
Bioinformatics 22, 2005-2011
   Abstract »    Full Text »    PDF »
Unique effects of Stat3 on the early phase of hematopoietic stem cell regeneration.
Y.-J. Chung, B.-B. Park, Y.-J. Kang, T.-m. Kim, C. J. Eaves, and I.-H. Oh (2006)
Blood 108, 1208-1215
   Abstract »    Full Text »    PDF »
Genome-Wide Transcriptional Profiling of Human Embryonic Stem Cells Differentiating to Cardiomyocytes.
A. Beqqali, J. Kloots, D. Ward-van Oostwaard, C. Mummery, and R. Passier (2006)
Stem Cells 24, 1956-1967
   Abstract »    Full Text »    PDF »
Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors.
I. Kim, S. He, O. H. Yilmaz, M. J. Kiel, and S. J. Morrison (2006)
Blood 108, 737-744
   Abstract »    Full Text »    PDF »
Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction.
C. S. Wilson, G. S. Davidson, S. B. Martin, E. Andries, J. Potter, R. Harvey, K. Ar, Y. Xu, K. J. Kopecky, D. P. Ankerst, et al. (2006)
Blood 108, 685-696
   Abstract »    Full Text »    PDF »
Transcriptional Profiling of Enriched Populations of Stem Cells Versus Transient Amplifying Cells: A COMPARISON OF LIMBAL AND CORNEAL EPITHELIAL BASAL CELLS.
M. Zhou, X.-m. Li, and R. M. Lavker (2006)
J. Biol. Chem. 281, 19600-19609
   Abstract »    Full Text »    PDF »
Gene Expression Profiles in Murine Hematopoietic Stem Cells Revisited: Analysis of cDNA Libraries Reveals High Levels of Translational and Metabolic Activities.
A. Huttmann, U. Duhrsen, K. Heydarian, L. Klein-Hitpass, T. Boes, A. W. Boyd, and C.-L. Li (2006)
Stem Cells 24, 1719-1727
   Abstract »    Full Text »    PDF »
Identification and Functional Analysis of Candidate Genes Regulating Mesenchymal Stem Cell Self-Renewal and Multipotency.
L. Song, N. E. Webb, Y. Song, and R. S. Tuan (2006)
Stem Cells 24, 1707-1718
   Abstract »    Full Text »    PDF »
Epithelial stem cells of the lung: privileged few or opportunities for many?.
E. L. Rawlins and B. L. M. Hogan (2006)
Development 133, 2455-2465
   Abstract »    Full Text »    PDF »
Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells.
R. D. Unwin, D. L. Smith, D. Blinco, C. L. Wilson, C. J. Miller, C. A. Evans, E. Jaworska, S. A. Baldwin, K. Barnes, A. Pierce, et al. (2006)
Blood 107, 4687-4694
   Abstract »    Full Text »    PDF »
Persistent Transactivation by Meis1 Replaces Hox Function in Myeloid Leukemogenesis Models: Evidence for Co-Occupancy of Meis1-Pbx and Hox-Pbx Complexes on Promoters of Leukemia-Associated Genes.
G. G. Wang, M. P. Pasillas, and M. P. Kamps (2006)
Mol. Cell. Biol. 26, 3902-3916
   Abstract »    Full Text »    PDF »
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells.
M. Pritsker, N. R. Ford, H. T. Jenq, and I. R. Lemischka (2006)
PNAS 103, 6946-6951
   Abstract »    Full Text »    PDF »
Hematopoietic-Osteoblastic Interactions in the Hematopoietic Stem Cell Niche.
L. M. Calvi (2006)
IBMS BoneKEy 3, 10-18
   Abstract »    Full Text »    PDF »
Molecular Profile and Partial Functional Analysis of Novel Endothelial Cell-Derived Growth Factors that Regulate Hematopoiesis.
J. P. Chute, G. G. Muramoto, H. K. Dressman, G. Wolfe, N. J. Chao, and S. Lin (2006)
Stem Cells 24, 1315-1327
   Abstract »    Full Text »    PDF »
Osteoblastic Activation in the Hematopoietic Stem Cell Niche.
L. M. CALVI (2006)
Ann. N.Y. Acad. Sci. 1068, 477-488
   Abstract »    Full Text »    PDF »
Human Side Population Keratinocytes Exhibit Long-Term Proliferative Potential and a Specific Gene Expression Profile and Can Form a Pluristratified Epidermis.
G. Larderet, N. O. Fortunel, P. Vaigot, M. Cegalerba, P. Maltere, O. Zobiri, X. Gidrol, G. Waksman, and M. T. Martin (2006)
Stem Cells 24, 965-974
   Abstract »    Full Text »    PDF »
Defining a Developmental Path to Neural Fate by Global Expression Profiling of Mouse Embryonic Stem Cells and Adult Neural Stem/Progenitor Cells.
K. Aiba, A. A. Sharov, M. G. Carter, C. Foroni, A. L. Vescovi, and M. S.H. Ko (2006)
Stem Cells 24, 889-895
   Abstract »    Full Text »    PDF »
The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets.
H. B. Sieburg, R. H. Cho, B. Dykstra, N. Uchida, C. J. Eaves, and C. E. Muller-Sieburg (2006)
Blood 107, 2311-2316
   Abstract »    Full Text »    PDF »
Stringent Regulation of DNA Repair During Human Hematopoietic Differentiation: A Gene Expression and Functional Analysis.
T. U. Bracker, B. Giebel, J. Spanholtz, U. R. Sorg, L. Klein-Hitpass, T. Moritz, and J. Thomale (2006)
Stem Cells 24, 722-730
   Abstract »    Full Text »    PDF »
Global Gene Expression Profile of Human Cord Blood-Derived CD133+ Cells.
T. Jaatinen, H. Hemmoranta, S. Hautaniemi, J. Niemi, D. Nicorici, J. Laine, O. Yli-Harja, and J. Partanen (2006)
Stem Cells 24, 631-641
   Abstract »    Full Text »    PDF »
Human Umbilical Cord Matrix Stem Cells: Preliminary Characterization and Effect of Transplantation in a Rodent Model of Parkinson's Disease.
M. L. Weiss, S. Medicetty, A. R. Bledsoe, R. S. Rachakatla, M. Choi, S. Merchav, Y. Luo, M. S. Rao, G. Velagaleti, and D. Troyer (2006)
Stem Cells 24, 781-792
   Abstract »    Full Text »    PDF »
Differential mRNA Processing in Hematopoietic Stem Cells.
T. V. Bowman, A. J. McCooey, A. A. Merchant, C. A. Ramos, P. Fonseca, A. Poindexter, S. B. Bradfute, D. M. Oliveira, R. Green, Y. Zheng, et al. (2006)
Stem Cells 24, 662-670
   Abstract »    Full Text »    PDF »
Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.
C. J. Luckey, D. Bhattacharya, A. W. Goldrath, I. L. Weissman, C. Benoist, and D. Mathis (2006)
PNAS 103, 3304-3309
   Abstract »    Full Text »    PDF »
Inseparably Tied: Functional and Antioxidative Capacity of Endothelial Progenitor Cells.
J. Haendeler and S. Dimmeler (2006)
Circ. Res. 98, 157-158
   Full Text »